A Study on the effect of Alpha and Beta adrenergic receptors on the Electro�Magnetic Field )EMF( analgesia

Subject Areas : clinical veterinary science

M.R Rahimnejad ¹ , رامین Hajikhani ²

1 - Department of Basic Science, Faculty of Veterinary Medicine, Islamic Azad University, Karaj Branch, Karaj, Iran.
2 - Department of Basic Science, Faculty of Veterinary Medicine, Islamic Azad University, Karaj Branch, Karaj, Iran

Received: 2016-11-02 Accepted : 2016-11-02 Published : 2011-03-21

Keywords: pain, α Adrenergic, β Adrenergic, EMF,

Abstract :

This study has been performed on ten quintet groups of mice. In fact, the role of adrenergic system on the effectof EMF on acute pain sensation has been examined treating with four drugs (yohimbine, xylazine, propranololand salbutamol). The animals were divided into two groups, the frst group were exposed to EMF (one hour in aday for 7 days), whereas the second group weren’t exposed to EMF. Both groups were treated with the drugs (IP)separately.The results revealed that Yohimbin (α2 Blocker) decreased and Xylazine (α2 Agonist) increased the analgesic effect of EMF on chronic pain but Propranolol (β1, β2, β3 Blocker) and Salbutamol (β2 Agonist) didn’t show anysignifcant different in analgesic effect of EMF on acute pain.In conclusion we can say that the EMF has the antinociceptive effect on the chronic pain threshold via adrenergicsystem.