بررسی اثر تزریق وریدی استامینوفن(آپوتل) در تسکین درد پس از عمل ابدومینوپلاستی

Subject Areas : علوم پزشکی

Naser Sanjar Mousavi ¹ , Rozita Khalili ²

1 - استادیار، دانشکده پزشکی، دانشگاه آزاد اسلامی مشهد، مشهد، ایران.
2 - دانشجوی رشته پزشکی، دانشکده پزشکی، دانشگاه ازاد اسلامی مشهد، مشهد، ایران.

Received: 2017-06-05 Accepted : 2017-06-05 Published : 2014-05-22

Keywords: pain, Intravenous Acetaminophen, Abdominoplasty, Pain scale,

Abstract :

Background:Pain management is a crucial component in the postoperative care of patient.  Opioids,which have been the mainstay of  postoperative pain control for some time, are being used less because of significant adverse effects. Recently Intravenous acetaminophen that is a analgesic and antipyretic drug  is used for reduce postoperative pain. Objective: Efficacy of  Intravenous Acetaminophen (Apotel) in control of pain after abdominoplasty. Methods: In this clinical trial 60 patients who underwent abdominoplasty and were willing to participate in this research project were randomly divided into two groups A and B.After the patient is awaked the pain based VLAS scoring system recording in the questionnaire, in A group we used intravenous acetaminophen 1000 mg , Acetaminophen was administered every 6 hours up to 4 times and the pain in injection time and three hours after injection was record. Due to ethical considerations and the rights of patients, despite taking acetaminophen if the patient still had pain we used other methods such as intramuscular injection of 10 mg methadone or 100 mg diclofenac suppository. In group B, conventional methods of pain relief in patients with an intramuscular injection of 10 mg of methadone and diclofenac suppository mg 100 was used. Assessment of pain in these patients during and three hours after injection were performed. Results: In general, pain was different in the two groups and greater pain reduction was observed in the control group and the difference was statistically significant (p=0/024). the total amount of opioid that was, methadone 70 mg in acetaminophen group and methadone 1200 mg in control group, be differed. Also taking diclofenac as an analgesic supplement distributed 30% in the acetaminophen group and 50% in the control group (p=0/114). After review of adverse events in both groups no significant difference was found between the two groups (p>0/05).Alpha Conclusion: According to the information obtained, Intravenous acetaminophen is effective in reduction of postoperative pain after abdminoplasty and reducing opioids consumption. Therefore can be appropriate and available alternative of opioids in postoperative relieving pain.    

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