Effect of Eight Weeks Resistance Training on Serum Levels of Hepatic Enzymes Including AST, ALT and ALP in Overweight Mens with Nonalcoholic Fatty Liver Disease

Subject Areas : Journal of Animal Biology

S. Nejadsalim ¹ , M. Gholami ²

1 - Department of Exercise Physiology, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of Exercise Physiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

Received: 2018-04-04 Accepted : 2018-08-10 Published : 2018-08-23

Keywords: Resistance training, Fatty liver, Hepatic enzyme, Steatosis,

Abstract :

The effect of different types of exercise training in patients with nonalcoholic fatty liver disease (NAFLD) is unclear. Therefore, the aim of present study was to investigate the effect of eight weeks’ resistance training on serum levels of hepatic enzymes' including AST, ALT and ALP in overweight men’s afflicted by NAFLD. For this purpose, 30 overweight men’s afflicted by NAFLD with average age 40.2 ± 2.5 and weight 75.5 ± 3.19 randomly divided in control (n=15) and resistance training (n=15) groups. Subjects in training group take part in resistance training program for eight weeks and three sessions per week. Training intensity increased from 40 percent of 1RM in first week to 70 percent of 1RM in last week. Blood samples collected in the end of research protocol and given variables measured in serum. Present study result analyzed by SPSS-24 software and using analyze covariance (ANCOVA) test. Results indicated that serum levels of AST (p= 0.024) and ALT (p= 0.006) significantly decreased in resistance training group, but changes in serum levels of ALP wasn’t significant (p= 0.096). Moreover, result indicated significant improvement of lipid profile in trained group (p= 0.001). According to present study result, positive effect of resistance training in patient with NAFLD may be exert by decreasing levels of hepatic enzyme and this training program can play effective role in modulating lipid profile in patient with NAFL.

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