Preparation of Double-layer Nanofibers Base on Hydrogel, Silver nanoparticles, and Fatty Acid using electrospinning technique

Subject Areas :

ensieh ghasemian lemraski ¹ ( faculty of science, Ilam University, Ilam, Iran )
elaheh khajehali ² ( Department of Chemistry, faculty of Para-veterinary, Ilam University (69315-516), Pajuhesh Blv., Ilam, )
sahar yari ³ ( 1 Department of Chemistry, Faculty of Science, Ilam University (69315-516), Pajuhesh Blv., Ilam, Iran )

Received: 2021-10-07 Accepted : 2022-01-15 Published : 2022-05-22

Keywords: polymer, silver nanoparticles, fatty acid, Chitosan, Nanofibers,

Abstract :

Today, electrospinning method is widely used to produce nanofibers based on polymers. Poly (vinyl-alcohol) and chitosan are among the most widely used polymers in biochemistry and medicine, especially in wound healing and tissue engineering. In this project, an attempt has been made to make polymeric materials and silver nanoparticles, nanofibers with protection and antimicrobial capabilities. Electrospinning method for making bilayer nanofibers, top layer containing poly (vinyl alcohol) and chitosan containing silver nanoparticles or silver ions as antimicrobial layer, and bottom layer containing polyvinylpyrrolidone and fatty acid as layer Moisturizes the skin of injured skin. Morphology and structure of nanofibers produced using various methods such as XRD X-ray spectroscopy, FTIR infrared Fourier transform spectroscopy, thermal weighing method or TGA, X-ray energy diffraction spectroscopy (EDAX-EDS), electron microscopy method (SEM), and finally the transmission electron microscopy (TEM) method was examined. The results of the instrumental analysis indicate the production of polymer fibers with a diameter in the range of 200-500 nanometers, which indicates the successful production of nanofibers, and also structural analyzes confirm the presence of silver nanoparticles and silver ions. The results of microbial tests show that nanofibers containing silver ions have a greater antimicrobial effect than silver nanoparticles.

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