• فهرس المقالات Heart failure

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        1 - The impact of sodium intake on anthropometric indices in acute heart failure patients admitted to Tehran Shahid Rajaei Hospital
        Fatemeh Asadi Seyedeh Baran Hashemi Abolghassem Djazayery
        Heart failure occurs when the heart is unable to pump enough blood to the body's organs. Sodium intake has many side effects but is also necessary for health. Previous studies on sodium intake have shown inconsistent results, and to our knowledge, no studies have been c أکثر
        Heart failure occurs when the heart is unable to pump enough blood to the body's organs. Sodium intake has many side effects but is also necessary for health. Previous studies on sodium intake have shown inconsistent results, and to our knowledge, no studies have been conducted on this topic in Iran. Therefore, we decided to study the relationship between sodium intake and anthropometric indices in patients with acute heart failure in Tehran in 2021. The study was conducted on 114 patients with acute heart failure aged 16 to 80 admitted to Shahid Rajaei Hospital in Tehran. Demographic information and data related to sodium intake were collected using questionnaires, and anthropometric measurements were made using standard methods. More than half (54.4%) of the patients were men, and 45.6% were women, with an average age of 62. SPSS version 26 software was used for data analysis, and a P-value <0.05 was considered statistically significant. Spearman's correlation test measured the relationship between sodium intake and anthropometric indices. There were no statistically significant differences or correlations between sodium intake and anthropometric indices in patients with acute heart failure تفاصيل المقالة
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        2 - Effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise
        Nooshin Khajeian Mehrzad Moghadasi
        Introduction: Galectin-3 (gal-3) is a member of the lectin family that is associate with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and ventricular remodeling. Although gal-3 increases after high intensity exercise, أکثر
        Introduction: Galectin-3 (gal-3) is a member of the lectin family that is associate with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and ventricular remodeling. Although gal-3 increases after high intensity exercise, regular training may attenuate these conditions. The aim of present study was to investigate the effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise. Material & Methods: Elevenhealthy young men (aged: 20.8 ± 1.8 years; ± SD) volunteered to participate in this study. All the subjects were performed Repeated High-Intensity Endurance Test (RHIET) as a strenuous aerobic exercise. Thereafter, the subjects were performed endurance training 3 days a week for 8 weeks at an intensity corresponding to 60-75% individual heart rate reserve (HRR) for 30-45 min. After the 8 weeks intervention, the RHIET was performed a gain. Blood samples were taken at baseline (1st step), immediately after the RHIET (2nd step), 48h after 8 weeks intervention (3rd step) and immediately after the second RHIET (4th step). Results: The results showed that gal-3 level was increased after the first strenuous aerobic exercise (P<0.05). After 8 weeks exercise training, gal-3 was decreased compared to 2nd step of blood sampling (P<0.05) and no significant change was observed in gal-3 in this step compare to the baseline. The results indicated that gal-3 level was lower after the second strenuous aerobic exercise than compare to the after the first strenuous aerobic exercise (P<0.05). Conclusions: The results suggest regular endurance training with specific intensity and duration utilized in this study, attenuate gal-3 changes after single session of strenuous aerobic exercise. تفاصيل المقالة
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        3 - Galectin-3 concentrations in response to an exhaustive aerobic exercise
        Mohammad Ghassami Saeid Naraghi
        Introduction: Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensate heart failure and chronic heart failure populations. Although endurance exercise is a crucial element in cardiovascular diseas أکثر
        Introduction: Elevated levels of galectin-3 have been found to be significantly associated with higher risk of death in both acute decompensate heart failure and chronic heart failure populations. Although endurance exercise is a crucial element in cardiovascular disease prevention, the relationship between exercise and plasma levels of galectin-3 is still unknown. The aim of this study was to determine the effect of an exhaustive aerobic exercise on galectin-3 levels in healthy males. Material & Methods: Fifteen healthy male (aged: 22.2 ± 2.3 years; ± SD) volunteered to participate in this study. The subjects were performed Bruce protocol as the exhaustive aerobic exercise. The blood sample was taken before and immediately after the completion of the exhaustive aerobic exercise. Wilcoxon test and Spearman correlation test were used to analyze the data. Results: The results demonstrated that galectin-3 had no significant changes in response to the exhaustive aerobic exercise (297.6 ± 180.5 vs. 294.9 ± 190.3 pg/ml). No significant correlation was observed between the post-exercise levels of galectin-3 with body mass (r = 0.1, P = 0.7), BMI (r = ‒ 0.1, P = 0.7), body fat percentage (r = 0.06, P = 0.8), WHR (r = 0.02, P = 0.9), or VO2max (r = 0.2, P = 0.4). Conclusions: In conclusion, the exhaustive aerobic exercise had not significant effects on galectin-3 concentrations in healthy individuals. تفاصيل المقالة
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        4 - The effect of an exhaustive aerobic exercise on NT-proBNP levels in healthy males
        Mohammad Ghassami Saeid Naraghi
        Introduction: Many studies documented the relationship between elevated plasma concentrations of brain natriuretic peptide (BNP) and its aminoterminal propeptide (NT-proBNP) and cardiovascular diseases, especially heart failure (HF). However, it is still uncertain wheth أکثر
        Introduction: Many studies documented the relationship between elevated plasma concentrations of brain natriuretic peptide (BNP) and its aminoterminal propeptide (NT-proBNP) and cardiovascular diseases, especially heart failure (HF). However, it is still uncertain whether physical exercise leads to a significant release of NT-proBNP in healthy subjects. The aim of this study was to determine the effect of an exhaustive aerobic exercise on NT-proBNP levels in healthy males. Material & Methods: In this study, Fifteen healthy male (aged: 22.2 ± 2.3 years; ± SD) volunteered to participate in this study. The subjects were performed Bruce protocol as the exhaustive aerobic exercise. NT-proBNP plasma concentrations were measured before and immediately after the exhaustive aerobic exercise. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the exhaustive aerobic exercise (P<0.05). We did not find any correlation between the post-exercise increase of NT-proBNP levels and body mass index (BMI), body fat percentage (%BF) or VO2max. Conclusions: In conclusion, the exhaustive aerobic exercise in healthy individuals led to a fast rise of plasma NT-proBNP concentrations. تفاصيل المقالة
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        5 - عوامل موثر در تبعیت از رژیم درمانی و ارتباط باور بهداشتی و آگاهی با آن در بیماران زن مبتلا به نارسایی قلبی
        نایله عزتی
        نارسایی قلبی از شایع‌ترین بیماری‌های مزمن دنیا است وهزینه‌های زیادی به سیستم‌های بهداشتی دارد. ارتقای پذیرش رژیم درمانی روش موثر در پیشگیری از نارسایی قلبی و افزایش بقای بیماران است. این مطالعه با هدف بررسی درمان و باور بهداشتی و آگاهی در بیماران مبتلا به نارسایی قلب ان أکثر
        نارسایی قلبی از شایع‌ترین بیماری‌های مزمن دنیا است وهزینه‌های زیادی به سیستم‌های بهداشتی دارد. ارتقای پذیرش رژیم درمانی روش موثر در پیشگیری از نارسایی قلبی و افزایش بقای بیماران است. این مطالعه با هدف بررسی درمان و باور بهداشتی و آگاهی در بیماران مبتلا به نارسایی قلب انجام گرفت.این پژوهش یک مطالعه توصیفی همبستگی بود که 250 بیمار مبتلا به نارسایی قلبی پرسش‌نامه‌ها را تکمیل کردند. پرسش‌نامه‌ها شامل 4 بخش متغیرهای دموگرافیک و بالینی، پرسش‌نامه اصلاح شده تبعیت درمان نارسایی قلب، مقیاس آگاهی و باور نارسایی قلب بود. در تجزیه و تحلیل داده‌ها از نرم افزار SPSS 22 آمار توصیفی و استنباطی، تی مستقل، آنووا، خی دو، ضریب همبستگی پیرسون، رگرسیون لجستیک استفاده شد. اکثریت واحدهای پژوهش دارای پذیرش متوسط از رژیم درمانی بوده و اکثریت آگاهی از نارسایی قلب داشتند. در این پژوهش بین باور بیماران از منافع و منابع پذیرش درمان ارتباط معنی‌دار مشاهده گردید نتایج حاکی از آن بود که میان تبعیت رژیم درمانی و برخی مشخصات دموگرافیک ارتباط معنی‌دار آماری وجود داشت. نتایج پژوهش نشان داد که تبعیت در حیطه‌های رژیم دارویی، محدودیت سدیم و قرار ملاقات با پزشک بالا بود. اکثریت بیماران آگاهی کمی درباره بیماری خود و رژیم نارسایی قلب داشتند. تاکید بر روش های خودمراقبتی مانند توزین روزانه، توضیح بیمار درباره چگونگی توجه به خودکنترلی در راستای پیشگیری از تشدید علایم نارسایی قلب از اهمیت بسزایی برخوردار است. مداخلات درمانی و مراقبتی در راستای مشکلات تجربه شده بیماران طراحی شوند.واژه های کلیدی: تبعیت، رژیم درمانی ، باور بهداشتی، آگاهی، بیماری نارسایی قلبی تفاصيل المقالة
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        6 - مقایسه اثر تمرینات هوازی تناوبی و تداومی به همراه تمرین مقاومتی دمی بر اپلین 17 و سیستم رنین آنژیوتانسین در مردان مبتلا به نارسایی قلبی
        حمید طالبی فرد حبیب اصغرپور رضا رضایی شیرازی عبدالامیر سیاری
        مقدمه و هدف: تمرینات هوازی از مداخلات مبتنی بر بازتوانی قلبی در بیماری نارسایی قلبی است. هدف تحقیق حاضر مقایسه اثر تمرینات هوازی تناوبی و تداومی به همراه تمرین مقاومتی دمی بر اپلین 17 و سیستم رنین آنژیوتانسین در مردان مبتلا به نارسایی قلبی بود.مواد و روش‌ها: در تحقیق نی أکثر
        مقدمه و هدف: تمرینات هوازی از مداخلات مبتنی بر بازتوانی قلبی در بیماری نارسایی قلبی است. هدف تحقیق حاضر مقایسه اثر تمرینات هوازی تناوبی و تداومی به همراه تمرین مقاومتی دمی بر اپلین 17 و سیستم رنین آنژیوتانسین در مردان مبتلا به نارسایی قلبی بود.مواد و روش‌ها: در تحقیق نیمه تجربی حاضر 30 مرد مبتلا به نارسایی قلبی به صورت تصادفی به 3 گروه تمرین هوازی تناوبی، تمرین هوازی تداومی وکنترل تقسیم شدند. مداخله تمرین شامل هشت هفته تمرینات هوازی فزاینده یا تناوبی در 2 وهله 10 دقیقه ای تریدمیل و ارگومتر با شدت 85-40 درصد ضربان قلب ذخیره و در ادامه تمرین مقاومتی دمی با شدت با 70-40 درصد S-index بود. هردو پروتکل تمرین ایزوکالریک بودند و فقط شیوه تمرینات هوازی در دو گروه متفاوت بود. از آزمون تحلیل کواریانس برای تجزیه و تحلیل آماری استفاده شد (05/0≥ P).یافته ها: پس از هشت هفته تمرین کاهش معنی داری در آنژیوتانسین I (001/0 > P) و افزایش معنی داری در سطوح آنژیوتانسین II (به ترتیب: 019/0 = P)؛ 013/0 = P) و آپلین 17 (001/0 > P) در گروه‌های تمرین تداومی و تناوبی نسبت به گروه کنترل مشاهده شد. همچنین تفاوت معنی داری بین دو گروه تمرین تداومی و تناوبی مشاهده نشد.نتیجه‌گیری: با توجه به نتایج می توان گفت که تمرینات ورزشی هوازی چه به صورت تداومی و چه به صورت تناوبی با افزایش اپلین اثرات مثبتی بر سیستم رنین آنژیوتانسین و در نتیجه بهبود عملکرد قلبی-عروقی در بیماران مبتلا به نارسایی قلبی دارد. تفاصيل المقالة
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        7 - Entropy Measures of Irregularity and Complexity for Surface Electrocardiogram Time Series in Patients with Congestive Heart Failure
        Chandrakar Kamath
        Congestive heart failure (CHF) remains to be one of the major cardiovascular disorders in the world. Due to the prevalence of CHF related issues, it is prudent to seek out new prognostic predictors that would facilitate the prevention, monitoring, and treatment of the d أکثر
        Congestive heart failure (CHF) remains to be one of the major cardiovascular disorders in the world. Due to the prevalence of CHF related issues, it is prudent to seek out new prognostic predictors that would facilitate the prevention, monitoring, and treatment of the disease on a daily basis. A detection approach using entropy measures extracted from surface electrocardiograms (ECGs) and classification for congestive heart failure (CHF) is presented in this paper. Four different entropies are used: approximate entropy (ApEn), sample entropy (SampEn), permutation entropy (PE), and energy entropy (EE). These entropies are employed to evaluate the irregularity and complexity of ECG time series and discuss the viability of recognizing CHF patients from normal subjects. Student’s t-tests and receiver operating characteristic (ROC) plots show that among the four entropies, EE outperforms other three entropies. These tests also indicate the feasibility of using surface ECGs to effectively discriminate CHF patients from normal subjects. تفاصيل المقالة
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        8 - Local Characteristic Decomposition as a Novel Approach to Predict Sudden Cardiac Death in Congestive Heart Failure Patients
        Ali Dorostghol Adel Maghsoudpour Ali Ghaffari Mansour Nikkhah-Bahrami
        The current study uses heart rate variability (HRV) signal processing to investigate changes in the multifractal dimension in congestive heart failure (CHF) patients and predict sudden cardiac death (SCD). In this regard, HRV signals are first extracted, and their four أکثر
        The current study uses heart rate variability (HRV) signal processing to investigate changes in the multifractal dimension in congestive heart failure (CHF) patients and predict sudden cardiac death (SCD). In this regard, HRV signals are first extracted, and their four sub-signals are determined using the Local Characteristic Decomposition (LCD) method. In the next step, using the Teager Energy method, the instant amplitudes of each sub-signal obtained in the previous step are calculated; thus, new signals are generated based on these instant amplitudes. Employing multifractal detrended fluctuation analysis (MF-DFA), the modified fractal dimensions of each new signal are then obtained. With the t-test method, appropriate features are selected and input into the support vector machine (SVM) classifier. By detecting subtle changes in HRV signals, this method can detect SCD in CHF patients. The results indicate that the proposed algorithm can distinguish the signals of SCD subjects with an accuracy of 84.76% 26 minutes before the event. In addition, after passing each 5-minute interval, the proposed method can update and determine how much time is left before SCD occurs تفاصيل المقالة
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        9 - Congestive Heart Failure from ECG Prediction Using Empirical wavelets transform Algorithm
        Nazanin Tataei Sarshar Mehdi Abdossalehi
        Heart diseases are the leading cause of death worldwide as such the use of an advanced information processing method to diagnose heart disease is one of the most critical fields of medical research. Among various heart diseases, congestive heart failure refers to a diff أکثر
        Heart diseases are the leading cause of death worldwide as such the use of an advanced information processing method to diagnose heart disease is one of the most critical fields of medical research. Among various heart diseases, congestive heart failure refers to a difficulty in the heart's pumping, and its symptoms vary depending on the body organ being the most involved in reducing pumping performance. Accordingly, several studies have been conducted to diagnose heart problems using Heart rate variability (HRV) analysis of cardiac signals even though the signals are not accurate enough. The HRV signal extracted from the ECG signal was analyzed to classify the Congestive heart failure’s signals and normal signals in the proposed method. Signal decomposition into a series of subbands was performed using Empirical Wavelets Transform (EWT), and the values ​​were calculated based on different subbands. In this case, the extracted features were classified by the SVM classification method. The method was used to classify normal individuals and those with CHF into two normal or abnormal groups. Finally, by implementing the proposed model and simulating the data of the PhysioNet site, the CHF problem could be automatically detected. The evaluation of the proposed method in comparison to other methods revealed that the proposed method has a significant advantage over other methods, as indicated by the accuracy value of 98.30.Heart diseases are the leading cause of death worldwide as such the use of an advanced information processing method to diagnose heart disease is one of the most critical fields of medical research. Among various heart diseases, congestive heart failure refers to a difficulty in the heart's pumping, and its symptoms vary depending on the body organ being the most involved in reducing pumping performance. Accordingly, several studies have been conducted to diagnose heart problems using Heart rate variability (HRV) analysis of cardiac signals even though the signals are not accurate enough. The HRV signal extracted from the ECG signal was analyzed to classify the Congestive heart failure’s signals and normal signals in the proposed method. Signal decomposition into a series of subbands was performed using Empirical Wavelets Transform (EWT), and the values ​​were calculated based on different subbands. In this case, the extracted features were classified by the SVM classification method. The method was used to classify normal individuals and those with CHF into two normal or abnormal groups. Finally, by implementing the proposed model and simulating the data of the PhysioNet site, the CHF problem could be automatically detected. The evaluation of the proposed method in comparison to other methods revealed that the proposed method has a significant advantage over other methods, as indicated by the accuracy value of 98.30. تفاصيل المقالة
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        10 - Lactobacillus paracasei Impact on Myocardial Hypertrophy in Rats with Heart Failure
        Zohreh Hesari Khatereh Kafshdoozan Mahdi Barati Parviz Kokhaei Sina Andalib Fatemeh TalebiKiassari Mahboubeh Darban anna abdolshahi Bahador Bagheri
        Cardiac hypertrophy and cardiac dysfunction are important complications of heart failure. Cardiovascular, immunological, and hormonal players are involved in the pathogenesis of heart failure. Current evidence suggests that probiotics may have fruitful effects on the he أکثر
        Cardiac hypertrophy and cardiac dysfunction are important complications of heart failure. Cardiovascular, immunological, and hormonal players are involved in the pathogenesis of heart failure. Current evidence suggests that probiotics may have fruitful effects on the heart function. This was our aim. To this end, effects of oral administration of Lactobacillus paracasei subsp. paracasei 8700:2 on isoproterenol-induced heart failure were investigated. Forty male Wistar rats weighing 200 g were randomly assigned to five groups; the control group (saline-treated group), probiotic-treated group, heart failure group (isoproterenol-introduced group), pretreatment group (treating them by probiotic for 20 days then induced heart failure) and treatment group (following heart failure-induced, treating them by probiotic for 20 days). The groups were studied for 30 days. Serum levels of atrial natriuretic peptide (ANP) and chemerin were measured by ELISA. Finally, the hearts were removed for histopathological evaluation. Compared to the control group, isoproterenol caused cardiac hypertrophy and increased ANP (P < 0.05) and chemerin levels. Treatment with Lactobacillus paracasei significantly reduced the levels of ANP (P < 0.01) and decreased the pathological damages to the myocardium. It caused a small reduction in chemerin level, as well. Pretreatment with probiotics had no positive effects on cardiac hypertrophy and related parameters. Our findings indicate that treatment with Lactobacillus paracasei subsp. paracasei 8700:2 reduces cardiac hypertrophy in rats. In addition, this probiotic reduces the serum levels of chemerin and ANP. تفاصيل المقالة
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        11 - The Influence of Overt Hyperthyroidism on the Plasma Level of β- type Natriuretic Peptide
        Ruqaya M. Al-sultan Hazim A. Mohammed
        Thyroid hormones (THs) have different effects on the heart and peripheral vascular system. Several changes occur across different status of thyroid dysfunctions. Overt hyperthyroidism (OHyper) induces significant changes in cardiac functions. Untreated OHyper is a cause أکثر
        Thyroid hormones (THs) have different effects on the heart and peripheral vascular system. Several changes occur across different status of thyroid dysfunctions. Overt hyperthyroidism (OHyper) induces significant changes in cardiac functions. Untreated OHyper is a cause of heart failure (HF). B-type Natriuretic Peptide (BNP) synthesized primarily in the myocardium. Thus, it is recommended as a diagnostic and prognostic marker for patients with HF. The present study was conducted to measure the effects of OHyper on the BNP level. A case-control study was conducted at a private clinic; Mosul Daily Surgical Clinic, Mosul, Nineveh, Iraq. From 1st Oct., 2020 to 1st Mar., 2021. Thirty (30) apparently healthy subjects with normal thyroid functions; Euthyroid (EU) subjects regarded as control group. Another newly diagnosed thirty (30) OHyper patients were enrolled in this study after exclusion of any facts that affect BNP level as cardiac disease, hypertension, patient taking angiotensin converting enzyme inhibitor, and pregnant ladies. They were diagnosed on the basis of thyroid function tests (TFTs); Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3) and Free Thyroxine (FT4). Plasma level of BNP were measured in OHyper and EU subjects’ group. Plasma BNP level is higher in patients with OHyper than EU individuals with mean values of 27.40± 35.59 and 21.68± 28.57 pg ml-1, (p>0.05) respectively. Moreover, there was a positive correlation between plasma BNP and serum FT4 level in EU (r=0.31, p=0.01) and in OHyper patients (r=0.57, P=0.001). OHyper affect plasma BNP level possibly influencing the secretion of this peptide. Therefore, thyroid functions have to be considered when evaluating any high plasma BNP level. تفاصيل المقالة