An overview of traditional medicinal plants as dengue virus inhibitors
Subject Areas : Medicinal and Herbal PlantsDluya Thagriki 1 , Upasana Ray 2
1 - CSIR-Indian Institute of Chemical Biology, 4, Raja S.C., Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India|Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India|Department of Biochemistry, Adamawa State University Mubi, Adamawa State, Nigeria-West Africa
2 - CSIR-Indian Institute of Chemical Biology, 4, Raja S.C., Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India|Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India
Keywords: Medicinal Plants, phytoconstituents, Dengue virus, Antiviral Activity,
Abstract :
Dengue fever has caused serious health problems around the world. Continents affected include Asia, Europe, North America, and Africa. Dengue fever, dengue hemorrhagic fever, and dengue shock syndrome are diseases caused by DENV. Promising antiviral activity of medicinal plants against DENV has been reported in several experimental studies. These plants are rich in bioactive constituents that have antiviral activity. This review extensively discussed the antiviral activity of these plants against DENV and the phytoconstituents responsible for the observed effects. The review discussed possible targets of these plant extracts or phytochemicals on the biological process of the virus as a potential mechanism for the observed inhibitory effects. Harnessing plants' chemical constituents can lead to the development of an antiviral against DENV.
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