Green synthesis of amide derivatives by using activated acetylenic compounds and amines

Subject Areas : Iranian Journal of Organic Chemistry

Received: 2023-08-08 Accepted : 2023-10-11 Published : 2023-10-30

Keywords: Lactams, Aniline, Naphthol amin, Dialkyl acetylenedicarboxylates,

Abstract :

The reaction between activated acetylenic compounds and various amines in the presence of Et3N leads to lactam derivatives in good yields. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification and performing without the catalyst.

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Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Green synthesis of amide derivatives by using activated acetylenic compounds and amines