Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes

الموضوعات : International Journal of Heterocyclic Chemistry

Mahsa Mahpeyma ¹ (Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran)
Bita Mohtat ² (Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran)

تاريخ الإرسال : 22 الأحد , شعبان, 1437 تاريخ التأكيد : 22 الأحد , شعبان, 1437 تاريخ الإصدار : 27 الأحد , جمادى الأولى, 1432

الکلمات المفتاحية: 3-hydroxy pyridine, dialkyl acetylene dicarboxylates, Alkyl isocyanide, multi component reaction, 4H-chromenes,

ملخص المقالة :

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good yields