SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION
الموضوعات : International Journal of Heterocyclic ChemistryBahram Pourhasan 1 , Mohammad Mahmudi Hashemi 2 , Ali Ezabadi 3
1 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
3 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
الکلمات المفتاحية: octahydroxanthene - thiamine chloride - solvent-free -dimedon,
ملخص المقالة :
A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.
