SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION

محورهای موضوعی : Journal of Chemical Reactivity and Synthesis

Bahram Pourhasan ¹ , Mohammad Mahmudi Hashemi ² , Ali Ezabadi ³

1 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
3 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

تاریخ دریافت : 1395/03/12 تاریخ پذیرش : 1395/03/12 تاریخ انتشار : 1391/02/12

کلید واژه: octahydroxanthene - thiamine chloride - solvent-free -dimedon,

چکیده مقاله :

A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.