SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION
الموضوعات : International Journal of Heterocyclic Chemistry
Bahram Pourhasan
1
(Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran;)
Mohammad Mahmudi Hashemi
2
(Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Ali Ezabadi
3
(Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran)
الکلمات المفتاحية: Solvent-free, octahydroxanthene, thiamine chloride, dimedon,
ملخص المقالة :
A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.
