SYNTHESIS OF 1,8-DIOXO-OCTAHYDROXANTHENES WITH THIAMINE CHLORIDE IN ECO-FRINDLY AND SOLVENT FREE CONDITION

محورهای موضوعی : Journal of Chemical Reactivity and Synthesis

Bahram Pourhasan ¹ , Mohammad Mahmudi Hashemi ² , Ali Ezabadi ³

1 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran;
2 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran
3 - Department of chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran

تاریخ دریافت : 1396/06/11 تاریخ پذیرش : 1396/09/01 تاریخ انتشار : 1396/09/25

کلید واژه: Solvent-free, octahydroxanthene, thiamine chloride, dimedon,

چکیده مقاله :

A novel, simple and environmentally friendly method is reported for the preparation of 1,8-dioxo-octahydroxanthene derivatives by the reaction of dimedon with various aromatic aldehydes, using thiamine chloride as a recyclable catalyst under solvent-free conditions. This procedure has following benefits; simple workup, moderate reaction times, good yields, and completely compatible with environment.