Effect of vitamin E supplementation on delayed onset muscle soreness in young men
الموضوعات : Journal of Physical Activity and Hormones
Mostafa Kashef
1
(MS in Exercise Physiology, Department of Physical Education, Shahid Bahonar Technical and Engineering College, Shiraz, Iran.)
الکلمات المفتاحية: vitamin E, C reactive protein, Delayed onset muscle soreness, Creatine kinase, Peak power of lower body,
ملخص المقالة :
Introduction: It has been hypothesized that markers of delayed onset muscle soreness (DOMS) induced by eccentric training could be decreased by supplementing subjects with vitamin E. Hence, this study was carried out to investigate the effect of vitamin E supplementation on DOMS indexes. Material & Methods: Twenty healthy male age 19 to 27 years participated as subjects in this study. The subjects were assigned to either a supplemental (400 IU of vitamin E per day for one month; n=10 and 22.4 ± 2.5 years of age) or a placebo group (n=10 and 22.7 ± 2.7 years of age) using a double-blind research design. peak power (PP) of Lower body, perceived pain, serum activity of the enzyme creatine kinase (CK) and C reactive protein (CRP) were taken before, immediately and 48 hours after the eccentric exercise. Results: The results indicated that perceived pain and serum levels of CK and CRP increased and PP of Lower body decreased significantly immediately after eccentric exercise in the both groups and these changes to be continued until 48 h after the intervention. No significant differences were observed between supplemental and placebo group during the study. Conclusion: In conclusion, vitamin E supplementation had no effect in ameliorating markers of DOMS induced by eccentric exercise. Further studies are needed to examine the effects of vitamin E supplementation on DOMS induced by eccentric exercise.
1. Connolly DA, Sayers SP, McHugh MP. Treatment and prevention of delayed onset muscle soreness. J Strength Cond Res 2003; 17: 197-208.
2. Nosaka K. Muscle soreness and damage and the repeated –bout effect In: Tiidus, P.M. (ed) Skeletal muscle damage and repaire, Champaign : Human Kinetics. 2008: 63-65.
3. Safran M, Zachazewski J, Benedetti R, Bartolozzi AR 3rd, Mandelbaum R. Lateral ankle sprains: a comprehensive review. Part 2: treatment and rehabilitation with an emphasis on the athlete. Med Sci Sports Exerc 1999; 31: 438-47.
4. Warren GL, Hayes DA, Lowe DA, Prior BM, Armstrong RB. Materials fatigue initiates eccentric contraction-induced injury in rat soleus muscle. J Physiol 1993; 464: 477-489.
5. Gleeson M, Almey J, Brooks S, Cave R, Lewis A, Griffiths H. Haematological and acute-phase responses associated with delayed-onset muscle soreness in humans. Eur J Appl Physiol Occup Physiol 1995; 71: 137-142.
6. Lieber RL, Woodburn TM, Fridén J. Muscle damage induced by eccentric contractions of 25% strain. J Appl Physiol (1985) 1991; 70: 2498-2507.
7. Edwards T, Baker S, Eston R. A method of detecting the muscle pain threshold using an objective software-mediated technique. Percept Mot Skills 1996; 82: 955-960.
8. Lukaski H. Vitamin and mineral status: effects on physical performance. Nutrition 2004; 20: 632- 644.
9. Mohammed SM, Jawis MN, Ahmed SA, Krasilshchikov O. Effects of dietary Vitamin C and E supplementation on exercise-induced muscle damage among young Kelantan weightlifters. J Biol Exerc 2015; 11: 41-53.
10. Silva L, Pinho C, Silveira P, Tuon T, De Souza C, Dal-Pizzol F, et al. Vitamin E supplementation decreases muscular and oxidative damage but not inflammatory response induced by eccentric contraction. J Physiol Sci 2010; 60: 51-57.
11. High DM, Howley ET, Franks BD. The effects of static stretching and warm-up on prevention of delayed-onset muscle soreness. Res Q Exerc Sport 1989; 60: 357-61.
12. Harman EA, Rosenstein MT, Frykmam PN, Rosenstein RM, Kraemer WJ. Estimation of human power output from vertical jump. J Appl Sport Sci Res 1991; 5: 116-120.
13. Friden J, Sjostrom J, Ekblom B. Myofibrillar damage following intense eccentric exercise in man. Int J Sports Med 1983; 4: 170-176.
14. Byrnes WC, Clarkson PM. Delayed onset muscle soreness and training. Clin Sports Med 1986; 5: 605-14.
15. Urso ML, Clarkson PM. Oxidative stress, exercise and antioxidant supplementation. Toxicology 2003; 189: 41-54.
16. Nedzvetsky VS, Tuzcu M, Yasar A, Tikhomirov AA, Baydas G. Effect of vitamin E against aluminum neurotoxicity in rats. Biochemistry (Mosc) 2006; 71: 239-244.
17. Serravite DH, Perry A, Jacobs KA, Adams JA, Harriell K, Signorile JF. Effect of whole-body periodic acceleration on exercise-induced muscle damage after eccentric exercise. Int J Sports Physiol Perform 2014; 9: 985-992.
18. Stupka N, Tarnopolsky MA, Yardley NJ, Phillips SM. Cellular adaptation to repeated eccentric exercise-induced muscle damage. J Appl Physiol (1985) 2001; 91: 1669-1678.
19. DiLorenzo FM, Drager CJ, Rankin JW. Docosahexaenoic acid affects markers of inflammation and muscle damage after eccentric exercise. J Strength Cond Res 2014; 28: 2768-2774.
20. Liao P, Zhou J, Ji LL, Zhang Y. Eccentric contraction induces inflammatory responses in rat skeletal muscle: role of tumor necrosis factor-alpha. Am J Physiol Regul Integr Comp Physiol 2010; 298: R599-R607.
21. Peake J, Nosaka K, Suzuki K. Characterization of inflammatory responses to eccentric exercise in humans. Exerc Immunol Rev 2005; 11: 64-85.
22. Fridén J, Lieber RL. Eccentric exercise-induced injuries to contractile and cytoskeletal muscle fibre components. Acta Physiol Scand 2001; 171: 321-326.
23. Beaton LJ, Allan DA, Tarnopolsky MA, Tiidus PM, Phillips SM. Contraction-induced muscle damage is unaffected by vitamin E supplementation. Med Sci Sports Exerc 2002; 34: 798-805.
24. Itoh H, Ohkuwa T, Yamazaki Y, Shimoda T, Wakayama A, Tamura S, et al. Vitamin E supplementation attenuates leakage of enzymes following 6 successive days of running training. Int J Sports Med 2000; 21: 369-374.
25. Dawson B, Henry GJ, Goodman C, Gillam I, Beilby JR, Ching S, et al. Effect of Vitamin C and E supplementation on biochemical and ultrastructural indices of muscle damage after a 21 km run. Int J Sports Med 2002; 23:10-15.
26. Petersen EW, Ostrowski K, Ibfelt T, Richelle M, Offord E, Halkjaer-Kristensen J, et al. Effect of vitamin supplementation on cytokine response and on muscle damage after strenuous exercise. Am J Physiol Cell Physiol 2001; 280: C1570-C1575.
27. Cannon JG, Orencole SF, Fielding RA, Meydani M, Meydani SN, Fiatarone MA, et al. Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release. Am J Physiol 1990; 259: R1214-R1219.
28. Raphael DJ, Hamadeh MJ, Tarnopolsky MA. Antioxidant supplementation attenuates the exercise-induced increase in plasma CK, but not CRP, during moderate intensity endurance exercise in men. FASEB J 2007; 21: 765-717.
29. Mastaloudis A, Traber M, Carstensen K, Widrick J. Antioxidants did not prevent muscle damage in response to an ultramarathon run. Med Sci Sports Exerc 2006; 38: 72-80.
30. Gaeini AA, Rahnama N, Hamedinia MR. Effects of vitamin E supplementation on oxidative stress at rest and after exercise to exhaustion in athletic students. J Sports Med Phys Fitness 2006; 46: 458-461.
