Optimal Control Strategy on Transmission Dynamics of HIV-HSV-II Coinfection Model
الموضوعات : مجله بین المللی ریاضیات صنعتی
Eshetu__Dadi__Gurmu Eshetu__Dadi__Gurmu
1
,
Boka__Kumsa__Bole Boka__Kumsa__Bole
2
,
Purnachandra __ Rao__Koya Purnachandra __ Rao__Koya
3
1 - Mathematics , Natural Science, Nekemte, Ethiopia
2 - Mathematics, Natural Science, Wollega University, Nekemte, Ethiopia
3 - Mathematics, Natural Science, Wollega University, Nekemte, Ethiopia
الکلمات المفتاحية: Coinfection, Stability, Optimal control, Numerical, Simulation,
ملخص المقالة :
In this paper, the optimal control problem is applied to Human immunodeficiency viruses (HIV) and Herpes simplex virus type 2 (HSV-2) coinfection model formulated by a system of ordinary differential equations. An optimal control system was performed with the help of the Runge-Kutta forward-backward sweep numerical approximation method. Finally, numerical simulation illustrated that a combination of all controls is the most effective strategy to minimize the disease from the community.
