Encapsulation of Tribulus terrestris and Valeriana officinalis Extracts in Nanoliposomes and Evaluation of its Antibacterial and Antioxidant Properties
الموضوعات :
M. Nouri
1
(Assistant Professor of the Department of Food Science and Technology, Roudehen Branch, Islamic Azad University, Roudehen, Iran.)
M. Shafaghi Rad
2
(MSc of Food Science and Technology, Roudehen Branch, Islamic Azad University, Roudehen, Iran.)
الکلمات المفتاحية: Antibacterial, antioxidant, Nanoliposomes, Tribulus terrestris, Valeriana officinalis,
ملخص المقالة :
One of the traditional medicine treatments is the use of medicinal herbs. Nanoliposomes have been utilized to improve the therapeutic properties. Tribulus terrestris and Valeriana officinalis are valuable native herbs in Iran. The aim of the present study was to improve and compare the functional properties of these herbs and in their nanoliposome forms. After extracting and production of nanoliposomes, antimicrobial and physicochemical, morphological properties and antioxidant activity were determined by disk diffusion and DPPH method, respectively. The loading capacity and encapsulation efficiency of the samples were 11.5 ± 0.6 % to 16.2 ± 0.3 % and 18.3 ± 0.7 % to 23.0 ± 0.2 %, respectively. The mean size of nanoliposomes particles containing Valeriana officinalis extract was 65.93 ± 4.1 nm, which were the largest particles with a significant difference. The highest mean of total phenolic content belonged to nanoliposomes containing Tribulus terrestris extract was 120.6 ± 1.5 (mg gallic acid/g extract). Among the microorganisms, Streptococcus iniae (20.51 ± 0.14 mm) and Staphylococcus aureus (19.17 ± 1.21 mm) had a higher inhibition zone as compared with other microorganisms. The results indicated that nanoliposomes increased the functional properties of Tribulus terrestris and Valeriana officinalis medicinal herbs.
Akbrian, A., Rahimmalek, M., Sabzalian, M. R. & Saeidi, G. (2017). Assessment of phytochemical, morphological and antioxidant variation of bilehar (Dorema aucheri) populations cultivated in different environmental conditions. Journal of Medicinal Plants, 16(2), 120-135.
Akram, M., Asif, H. M., Akhtar, N., Shah, P. A., Uzair, M., Shaheen, Gh., Tahira, Sh., Ali Shah, S. M. & Khalil, A. (2011). Tribulus terrestris Linn: A review article. Journal of Medicinal Plants Research, 5(16), 3601-3605.
Al Bayati, F. A. & Al Mola, H. F. (2008). Antibacterial and antifungal activities of different parts of T. terrestris L. growing in Iraq. Journal of Zhejiang University Science B, 9, 154-159.
Dehghani, S., Nouri, M. & Baghi, M. (2019). The effect of adding walnut green husk extract on antioxidant and antimicrobial properties of ketchup. Journal of Food and Bioprocess Engineering, 2(2), 93-100.
Fan, M., Xu, S., Xia, S. & Zhang, X. (2008). Preparation of salidroside nano-liposomes by ethanol injection method and in vitro release study. European Food Research and Technology, 227, 167-174.
Georgiev, G. I., Ivanova, A., Mechkarova, P., Ivanova, A. & Popova, L. (2010). Rate and forms of mineral nutrition CAN influence dry matter accumulation and saponin content of puncture vine (T. terrestris L.). Biotechnology and Biotechnological Equipment, 1(24), 49-52.
González-Paredes, A., Clarés-Naveros, B., Ruiz-Martínez, M. A., Durbán-Fornieles, J. J., Ramos-Cormenzana ,A. & Monteoliva-Sánchez, M. (2011). Delivery systems for natural antioxidant compounds: Archaeosomes and archaeosomal hydrogels characterization and release study. International Journal of Pharmaceutics, 421(2), 321-31.
Gulseren, I. & Corredig, M. (2013). Storage stability and physical characteristics of tea-polyphenolbearing nanoliposomes prepared with milk fat globule membrane phospholipids. Journal of Agricultural and Food Chemistry, 61, 3242-3251.
Hakemi, V. M., Goudarzi, H., Naseri, M. S., Kamalinejad, M., Jahangiri, S. & Gholami, M. (2013). In vitro assessment of Tribulus Terrestri aqueous extract and benzoxacin fraction against helicobacter pylori isolates from biopsy samples of Iranian patients. Novelty in Biomedicine, 3, 85-90.
Hematian, A., Nouri, M. & Safari, S. (2020). Effects of Capparis spinosa extract on kashk quality during storage. Foods and Raw Materials, 8(2), 402-410.
Khosravi Zanjani, M. A., Mohammadi, N., Zojaji, M. & Bakhoda H. (2015). Chemical composition of the essential oil of Mentha pulegium L. and its antimicrobial activity on Proteus mirabilis, Bacillus subtilis and Zygosaccharomyces rouxii. Journal of Food Biosciences and Technology, 5(2), 31-40.
Liolios, C., Gortzi, O., Lalas, S., Tsaknis, J. & Chinou, I. (2009). Liposomal incorporation of carvacrol and thymol isolated from the essential oil of Origanum dictamnus L. and in vitro antimicrobial activity. Food Chemistry, 112, 77-8336.
Lu, T. X., Shu, T., Qin, X. J., Ni, W., Ji, Y. H., Chen, Q. R., Khan, A., Zhao, Q. & Liu, H. Y. (2017). Spirostanol saponins from Ypsilandra parviflora induce platelet aggregation. Steroids, 123, 55-60.
Luximon Ramma, A., Bahorun, T., Soobrattee, M. A. & Aruoma, O. I. (2002). Antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of cassia fistula. Journal of Agricultural and Food Chemistry, 50, 5042-5047.
Moghimi, R., Ghaderi, L., Rafati, H., Ahmadi, A. & Mclements, D. J. (2016). Superior antibacterial activity of nanoemulsion of Thymus daenensis essential oil against E. coli. Food Chemistry, 194, 410-415.
Mohammed, M. J. (2008). Biological activity of saponins isolated from T. terrestris (fruit) on growth of some bacteria. Tikrit Journal of Pure Science, 13, 1-4.
Nandhini, S., Narayanan, K. B. & Ilango, K. (2018). Valeriana officinallis: A review of its traditional uses, phytochemistry and pharmacology. Asian Journal of Pharmaceutical and Clinical Research, 11, 36-41.
Naseri, L., Akbari bazm, M. & Khazaei, M. (2019). A review on therapeutic effects of Tribulus terrestris. Journal of Medicinal Plants, 18(72), 1-22.
NCCLS. (1999). Performance standards for antimicrobial susceptibility testing. 3th International Supplement, 100-109.
Nouri, M. & Khodaiyan, F. (2020). Green synthesis of chitosan magnetic nanoparticles and their application with poly-aldehyde kefiran cross-linker to immobilize pectinase enzyme. Biocatalysis and Agricultural Biotechnology, 29, 24-38.
Nouri, M. & Khodaiyan, F. (2021). Applications of nanoparticles containing ginger (Zingiber officinale) extract to improve the stability of encapsulated ginger. Journal of Food and Bioprocess Engineering, 4(1), 27-41.
Nouri, M. (2020). Preparation of nanoliposomes containing Hyssopus officinalisL. and EryngiumcaeruleumM.Bieb extractsand investigate their antimicrobial and antimicrobial effects. Journal of Medicinal Plants, 19(75), 118-131.
Pilerood, S. & Prakash, J. (2013). Nutritional and medicinal properties of valerian (Valeriana Officinalis) herb: A Review. International Journal of Food, Nutrition and Dietetics, 1, 25-32.
Pooyamanesh, M., Ahari, H., Anvar, A. A. & Karim, G. (2019). Synthesis and characterization of silver nanocomposite as a food packaging. Journal of Food Biosciences and Technology, 9(2), 73-82.
Rogerson, S., Riches, C. J., Jennings, C. & Weatherby, R. P. (2007). The effect of five weeks of T.terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. The Journal of Strength and Conditioning Research, 21, 348-353.
Semerdjieva, I. B. & Zheljazkov, V. D. (2019). Chemical constituents, biological properties, and uses of Tribulus terrestris: A review. Natural Product Communications, 14(8), 1–25.
Spigno, G., Donsì, F., Amendola, D., Sessa, M., Ferrari, G. & De Faveri, D. M. (2013). Nanoencapsulation systems to improve solubility and antioxidant efficiency of a grape marc extract into hazelnut paste. Journal of Food Engineering, 114, 207-214.
Wisuitiprot, W., Somsiri, A., Ingkaninan, K. & Waranuch, N. (2011). A novel technique for chitosan microparticle preparation using a water/silicone emulsion: Green tea model. International Journal of Cosmetic Science, 33, 351-358.
Xia, S. & Xu, S. (2005). Ferrous sulfate liposomes: preparation, stability and application in fluid milk. Food Research International, 38(3), 289-296.
Zakerin, A. R., Ahmadi, E., Fasihi Ramandi, M., Abdollahi, S., Molazadeh, A. R. & Jafari, S. (2015). The effects of ecologic condition on antimicrobial activity of endemic herbal extracts in fars province. Journal of Fasa University of Medical Sciences, 5(1), 111-119.
Zou, L. Q., Liu, W., Liu, W., Liang, R., Li, T. & Liu, C. (2014). Characterization and bioavailability of tea polyphenol nanoliposome prepared by combining an ethanol injection method with dynamic high-pressure microfluidization. Journal of Agricultural and Food Chemistry, 62, 934-941.
