The association of dietary acid load with non-alcoholic fatty liver disease among Iranian adults
الموضوعات :
Food and Health
Pegah Rahbarinejad
1
,
Maryam Mohamadi Narab
2
1 - Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
تاريخ الإرسال : 03 الثلاثاء , جمادى الثانية, 1441
تاريخ التأكيد : 16 السبت , رمضان, 1441
تاريخ الإصدار : 23 الإثنين , شوال, 1441
الکلمات المفتاحية:
Dietary acid load (DAL),
Non-alcoholic fatty liver dise,
Iranian adults,
ملخص المقالة :
Acid-base status, which can be affected by the dietary acid load (DAL), has been related to risk factors for non-alcoholic fatty liver (NAFLD). In the current study, we investigated the association between DAL and NAFLD among Iranian adults. This cross-sectional study was conducted on 675 participants, aged 20-60 years old. The dietary intake of participants was assessed using a validated semi-quantitative food frequency questionnaire, and the potential renal acid load (PRAL) and net endogenous acid production (NEAP) scores were calculated. Multiple logistic regression models were used to estimate the risk of NAFLD according to the PRAL and NEAP categories. The mean age of the participants was 38.1 ± 8.8 years old. The median of PRAL and NEAP were -8.13 and -9.05 mEq/day, respectively. In this study, the potential confounders including age, sex, leisure time activity, and total energy were adjusted in the multivariable-adjusted model. By using logistic regression, no significant association was observed between PEAL and NEAP with NAFLD. (OR=1.03, 95% CI: 0.66-1.60, P-value=0.905 and OR=1.12, 95% CI: 0.72-1.75, P-value=0.611, respectively) after adjustment for potential confounders. Longitudinal studies should be conducted to evaluate the association between PRAL and NEAP with NAFLD among adults.
المصادر:
Amarapurkar DN, Hashimoto E, Lesmana LA, Sollano JD, Chen PJ, Goh KL, et al. How common is non‐alcoholic fatty liver disease in the Asia–Pacific region and are there local differences? Journal of Gastroenterology and Hepatology. 2007;22(6):788-93.
Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH, Driscoll CJ. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology. 1999;29(3):664-9.
Bedogni G, Miglioli L, Masutti F, Tiribelli C, Marchesini G, Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology. 2005;42(1):44-52.
Who J, Consultation FE. Diet, nutrition and the prevention of chronic diseases. World Health Organ Tech Rep Ser. 2003;916(i-viii).
Setorki M, Nazari B, Asgary S, Azadbakht L, Rafieian-Kopaei M. Anti-atherosclerotic effects of verjuice on hypocholesterolemic rabbits. African Journal of Pharmacy and Pharmacology. 2011;5(8):1038-45.
Mozaffari H, Daneshzad E, Surkan PJ, Azadbakht L. Dietary total antioxidant capacity and cardiovascular disease risk factors: a systematic review of observational studies. Journal of the American College of Nutrition. 2018;37(6):533-45.
Mozaffari H, Namazi N, Larijani B, Surkan PJ, Azadbakht L. Associations between dietary insulin load with cardiovascular risk factors and inflammatory parameters in elderly men: a cross-sectional study. The British Journal of Nutrition. 2019;121(7):773-81.
Abshirini M, Siassi F, Koohdani F, Qorbani M, Mozaffari H, Aslani Z, et al. Dietary total antioxidant capacity is inversely associated with depression, anxiety and some oxidative stress biomarkers in postmenopausal women: a cross-sectional study. Annals of General Psychiatry. 2019;18(1):3.
Remer T, Dimitriou T, Manz F. Dietary potential renal acid load and renal net acid excretion in healthy, free-living children and adolescents. The American Journal of Clinical Nutrition. 2003;77(5):1255-60.
Remer T, Manz F. Estimation of the renal net acid excretion by adults consuming diets containing variable amounts of protein. The American Journal of Clinical Nutrition. 1994;59(6):1356-61.
Frassetto LA, Todd KM, Morris Jr RC, Sebastian A. Estimation of net endogenous noncarbonic acid production in humans from diet potassium and protein contents. The American Journal of Clinical Nutrition. 1998;68(3):576-83.
Zhang L, Curhan GC, Forman JP. Diet-dependent net acid load and risk of incident hypertension in United States women. Hypertension. 2009;54(4):751-5.
Ströhle A, Waldmann A, Koschizke J, Leitzmann C, Hahn A. Diet-dependent net endogenous acid load of vegan diets in relation to food groups and bone health-related nutrients: results from the German Vegan Study. Annals of Nutrition and Metabolism. 2011;59(2-4):117-26.
Scialla JJ, Anderson CA. Dietary acid load: a novel nutritional target in chronic kidney disease? Advances in Chronic Kidney Disease. 2013;20(2):141-9.
Maurer M, Riesen W, Muser J, Hulter HN, Krapf R. Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans. American Journal of Physiology-Renal Physiology. 2003;284(1):F32-F40.
Remer T, Pietrzik K, Manz F. Short-term impact of a lactovegetarian diet on adrenocortical activity and adrenal androgens. The Journal of Clinical Endocrinology & Metabolism. 1998;83(6):2132-7.
Chan R, Wong VW-S, Chu WC-W, Wong GL-H, Li LS, Leung J, et al. Higher estimated net endogenous Acid production may be associated with increased prevalence of nonalcoholic Fatty liver disease in Chinese adults in Hong Kong. PLoS One. 2015;10(4):e0122406.
Williams RS, Kozan P, Samocha-Bonet D. The role of dietary acid load and mild metabolic acidosis in insulin resistance in humans. Biochimie. 2016;124:171-7.
Krupp D, Johner SA, Kalhoff H, Buyken AE, Remer T. Long-term dietary potential renal acid load during adolescence is prospectively associated with indices of nonalcoholic fatty liver disease in young women. The Journal of Nutrition. 2012;142(2):313-9.
