ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction
الموضوعات : Iranian Journal of Catalysis
Javad Safaei-Ghomi
1
(Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.)
Hossein Shahbazi-Alavi
2
(Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.)
Mohammad Reza Saberi-Moghadam
3
(Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.)
Abolfazl Ziarati
4
(Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.)
الکلمات المفتاحية: Multi-component, One-pot, ZrP2O7 nanoparticles, N-amino-2-pyridones, 1, 2-Dihydropyridines,
ملخص المقالة :
ZrP2O7 nanoparticles (NPs) as an efficient catalyst have been used for the preparation of 1,6-diamino-2- oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via one-pot coupling of hyrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes under reflux conditions in ethanol. Using this method we obtained low reaction times, easy isolation of the targeted molecules, excellent yields.
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