ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction
محورهای موضوعی : Iranian Journal of CatalysisJavad Safaei-Ghomi 1 , Hossein Shahbazi-Alavi 2 , Mohammad Reza Saberi-Moghadam 3 , Abolfazl Ziarati 4
1 - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.
2 - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.
3 - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.
4 - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran.
کلید واژه: Multi-component, One-pot, ZrP2O7 nanoparticles, N-amino-2-pyridones, 1, 2-Dihydropyridines,
چکیده مقاله :
ZrP2O7 nanoparticles (NPs) as an efficient catalyst have been used for the preparation of 1,6-diamino-2- oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via one-pot coupling of hyrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes under reflux conditions in ethanol. Using this method we obtained low reaction times, easy isolation of the targeted molecules, excellent yields.
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