Thin layer chromatographic profiling and phytochemical analysis of hexane, ethyl acetate, n-butanol and aqueous fractions of Bombax costatum Pellgr. and Vuillet stem bark
Subject Areas : Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)Nuhu Mohammed 1 * , Jamilu Yau 2 , Aliyu Muhammad Musa 3
1 - Department of Clinical Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria;
2 - Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria;
3 - Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria;
Keywords: Bombax costatum, chromatography, phytochemical, zaria,
Abstract :
Background & Aim: Bombax costatum belongs to the family Bombacaceae. It is an important medicinal plant commonly found in savanna zones of West Africa. The plant is used in the treatment of liver diseases, epilepsy, malaria and microbial infections. This study was aimed to investigate the phytochemical compounds present in various fractions of stem bark of the plant. Experimental: Thin layer chromatographic profiling and phytochemical analysis of the hexane, ethyl acetate, n-butanol and residual aqueous fraction were carried out to explore the scientific basis for its ethno-medicinal value. Results: The results showed the presence of tannins and alkaloids in ethyl acetate, n-butanol and residual aqueous fractions. Flavonoid was present in only the ethyl acetate fraction. Triterpenes and steroids were found only in the hexane and ethyl acetate fractions while saponin was only present in the n-butanol and residual aqueous fractions of B. costatum stem bark. Anthraquinone was absent in all the fractions of stem bark. Recommended applications/industries: The presence of these phytochemicals supports the traditional use of B. costatum plant in the treatment of various diseases.
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