Synthesis of fumarate derivatives using multicomponent reaction of thioles

Subject Areas : Iranian Journal of Organic Chemistry

Received: 2023-11-15 Accepted : 2023-12-20 Published : 2024-01-18

Keywords: Fumarate, Activated acetylens, Thioles, Solvent-free, Arylisocyanate.,

Abstract :

The fumarate derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficient procedure utilizing activated acetylens, thioles and isocyanates in the presence of catalytic amount of Et3N under solvent-free conditions.

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Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Synthesis of fumarate derivatives using multicomponent reaction of thioles