One pot multi-component green synthesis of pyridine derivatives using malononitrile and efficient nanocatalyst
Subject Areas : Iranian Journal of Organic Chemistry
Keywords: Malononitrile, pyridines, dimethyl acetylenedicarboxylate, Fe3O4/ZnO nanoparticles, Multi-component reaction,
Abstract :
In this research, the Fe3O4/ZnO magnetic nanoparticles were synthesized through a green method using Petasites hybridus rhizome water extract as a reducing and stabilizing agent. The morphology and size of the Fe3O4/ZnO MCNPs was identified utilizing XRD, SEM and EDX analysis. The catalytic activity of the Fe3O4/ZnO MCNPs was evaluated in the efficient and green synthetic method for preparation of pyran drivatives in excellent yield via four component condensations of aromatic aldehyde, malononitrile, hydrazine and dimethyl acetylenedicarboxylate in water as green solvent. The turn over frequency (TOF) values of the catalysts are higher than some of the previously reported catalysts.