Synthesis of isoquinoline and quinoline derivatives using multicomponent reactions of ammonium acetate

Sharifi, Samanehsadat; Khandan, Samira

doi:10.30495/iranjoc.2023.699827

Manuscript ID : 699827 Visit : 162 Page: 3543 - 3546

10.30495/iranjoc.2023.699827

Article Type: Original Research

Synthesis of isoquinoline and quinoline derivatives using multicomponent reactions of ammonium acetate

Subject Areas : Iranian Journal of Organic Chemistry

Samanehsadat Sharifi ¹ , Samira Khandan ²

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Received: 2023-02-28 Accepted : 2023-02-28 Published : 2023-02-01

Keywords: ammonium acetate, Quinoline, Three-component reactions, Isoquinoline,

Abstract :

In this research, isoquinoline or quinolinethat reacts smoothly with activated acetylenic compounds in the presence of ammonium acetate to produce isoquinoline or quinoline derivatives. The advantages of this procedure than to reported methods are short time of reaction, high yields of product, easy separation of product, clean mixture of reaction and green media for performing reaction.

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Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Synthesis of isoquinoline and quinoline derivatives using multicomponent reactions of ammonium acetate