Synthesis of Novel imidazo[2,1-b]thiazoles from thiohydantoins and Diethyl oxalate

Subject Areas :

Mahboobeh Kiamarsi ¹ , Mohammad Mehdi Ghanbari ² , Marzieh Jamali ³ , Nasimeh Zarei ⁴ , Yalda Shaabani ⁵

1 - Young Researchers Club and Elite, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
2 - Young Researchers Club and Elite, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
3 - Young Researchers Club and Elite, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
4 - Young Researchers Club and Elite, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
5 - Young Researchers Club and Elite, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

Received: 2016-05-29 Accepted : 2016-05-29 Published : 2011-05-01

Keywords: Thiohydantoin, Diethyl oxalate, limidazo[2, 1-b]thiazoles, p-TSA, Antitumor,

Abstract :

Novel imidazo[2,1-b]thiazoles were synthesized in good yield via a mild reaction of thiophenytoin and diethyl oxalatein the presence of 10% mol p-TSA.

References:

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Synthesis of Novel imidazo[2,1-b]thiazoles from thiohydantoins and Diethyl oxalate