Surface-Modified Superparamagnetic Nanoparticles Fe3O4@PEG for Drug Delivery
Subject Areas : International Journal of Bio-Inorganic Hybrid Nanomaterials
Keywords: Superparamagnetism, Inverse micelle, Surface modification, Functionalize, Poly(ethyleneglycol), Nano magnetic,
Abstract :
In this work, we report on the synthesis of superparamagnetic iron oxide nanoparticles at room temperature using microemulsion template phase consisting of cyclohexane, water, CTAB as cationic surfactant and butanol as a cosurfactant. Surface modification have been carried out by using poly(ethyleneglycol) (PEG). The structure,morphology, and magnetic properties of the products were characterized by X-ray powder diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), and vibrating sample magnetometer (VSM) at room temperature. The results revealed formation of iron oxide nanoparticles, with an average size of 8.8-12 nm, a superparamagnetism behavior with fast response to applied magnetic fields and zero remanence and coercivity.