Nanoparticles bio production, considering their performance in medicine and biological science, is increasing; also, raising awareness of green chemistry and bioprocesses has encouraged the use of environmentally friendly methods for the production of non-toxic nanomaterials. Also uses of plants extracts are found to be more advantageous over chemical, physical and microbial (bacterial, fungal, algal) methods for silver nanoparticles (AgNPs) synthesis.The objectives of this study were the production of silver nanoparticles using aqueous and hydroalcoholic extracts of Avena sativa L. and investigation of the effect of extracts on the synthesis of nanoparticles. The morphology and size of the nanoparticles were determined using Scanning Electron Microscope (SEM) and UV-Vis spectroscopy. SEM images showed that the synthesized nanoparticles were mainly spherical and round shaped. The results indicated that synthesized nanoparticles using aqueous extract were better than the synthesized nanoparticles using hydro-alcoholic extract in shape and size. Synthesize silver nanoparticles using Avena sativa L. extract provides environmentally friendly option as compared to currently available chemical/ physical methods. پرونده مقاله

Biologically, two parameters of size and surface charge of the nanoparticles, especially therapeutic nanoparticles influence their kinetics in vivo as well as their interaction with the cellular and biological membranes and resulting their efficacy. So effective characterization of nanomaterials including nanometer-sized particles and micelles is a key issue to develop the well-deserved and well-defined Nano-formulations focus on the therapeutic goals in nanomedicine research. Determining the particle size and surface charge of nanoparticles are essential to characterize therapeutic nanoparticles properly. Measurements related to techniques of dynamic light scattering (DLS) and zeta potential (ZP) are known as easy, simple, and reproducible tools to obtain the size and surface charge of nanoparticles. Regarding characterization of particle size and surface charge by the DLS and ZP there is challenges for researchers to interpret and analyze the exported data effectively due to lack of adequate understanding focus on physical principles governing on the operating system of these techniques and how preparing samples for characterization and so on. With this in mind, this review tries to address this issue focus on the fundamental principles governing on techniques of DLS and ZP to better analyzing and interpreting the reported results such as hydrodynamic size, diffusion, inter particular interactions as well as study of the colloidal system stability based on surface charge of nanoparticles. پرونده مقاله

Metal oxide nanoparticles due to their antioxidant properties have attractedsignificant attention and exhibited good potential for use in cancer theranostics.Owing to the poor absorption in the physiological environment, they are anideal candidate to act as nanocarriers in targeted drug delivery and bioimaging.This feature can be successfully implemented in live monitoring and imagingapplications, which offer the possibilities and scope for optical, magneticresonance, and nuclear imaging. The environment of malignant cells likethe rapid proliferation of cells, specific antigen expressions, and leaky tumorvasculature can be used by the modifications in their morphology and surfacefunctionalization. Ceria (CeO2) nanoparticles have been fascinating in this regard.Different properties such as size, agglomeration behavior, and surface chargedensity facilitate the interaction of nanoparticles with cancer cells. Compared toother nanoparticles, CeO2 nanoparticles have a potential for pharmaceutical usesince they can act as a therapeutic agent in different disorders such as cancer,inflammation, and neurodegeneration, due to the ability to exhibit variableoxidation state at the nanoparticle surface. Recent literature reports the ecofriendlyor ‘green’ synthesis of CeO2 nanoparticles in which the biological agentacts as stabilizers for a cost-effective and feasible mode of preparation. In thisreview, we focus on recent literature on CeO2 nanoparticles with an emphasis onthe methods of fabrication and biomedical applications. پرونده مقاله

Nanoparticles bio production, considering their performance in medicine and biologicalscience, is increasing; also, raising awareness of green chemistry and bioprocesses hasencouraged the use of environmentally friendly methods for the production of non-toxicnanomaterials.. Also uses of plant extracts are found to be more advantageous over chemical,physical and microbial (bacterial, fungal, algal) methods for silver nanoparticles (AgNPs)synthesis. The objectives of this study were the production of silver nanoparticles using aqueous andhydroalcoholic extracts of Avena sativa L. an investigation of the effect of extracts on thesynthesis of nanoparticles. The morphology and size of the nanoparticles were determinedusing Scanning Electron Microscope (SEM) and UV-Vis spectroscopy. SEM images showed thatthe synthesized nanoparticles were mainly spherical and round shaped. The results indicatedthat synthesized nanoparticles using an aqueous extract were better than the synthesizednanoparticles using hydro-alcoholic extract in shape and size.Synthesize silver nanoparticles using Avena sativa L. Extract provides environmentally friendlyoption as compared to currently available chemical/ physical methods. پرونده مقاله