Background and Aim: Fibrosarcoma is a deadly tumor rarely derived from fibrous connective tissue. This malignant tumor grows slowly, and its main characteristics are the proliferation of immature fibroblasts or undifferentiated anaplastic spindle cells. The etiology of this tumor is unknown, while rarely leads to metastasis. A 3.5-year-old rabbit was referred to the veterinary clinic due to anorexia. After the examination, an ultrasound of the abdominal area was performed, which showed evidence of a tumor. The case was subsequently referred to radiography to investigate for any metastasis. After that, surgery was performed to remove the tumor mass from the ovaries and uterus, which weighed 120 grams. After taking a tissue sample and fixating it in a 10% buffered formalin buffer solution, it was referred to the pathology laboratory. The tissue was processed, sliced into 5-micron sections, and stained with Hematoxylin and Eosin as well as Masson's trichrome stainings. Our findings showed malignant changes such as spindle-shaped cells with unusual nuclei and mitotic figures, random growth patterns, and collagen fibers in all directions, in addition to the infiltration of inflammatory cells. Finally, the sample was diagnosed as fibrosarcoma. It should be noticed that regarding this tumor type, surgery is the recommended approach. However, if surgery is not possible, radiotherapy and chemotherapy can also be used. Same as this case, even after successful surgery, the animal should be monitored due to the possibility of recurrence. It should be noted that after 7 months, the animal's condition was reported to be good. پرونده مقاله

Cysticercus tenuicollis is the larval stage of the tapeworm Taenia. Taenia is a tapeworm that primarily infects dogs and other canids as its definitive hosts, and various ungulates (such as sheep, goats, and pigs) as intermediate hosts. The larval stage, Cysticercus tenuicollis, develops in the intermediate hosts. This study examined the causes of death in 14 lamb flocks of Mazandaran province, which were infected with acute cysticercosis. The causative agent was Cysticercus tenuicollis, the larval stage of the tapeworm Taenia hydatigena. This study examined instances of acute visceral cysticercosis in 14 lamb flocks located within Mazandaran province. This parasitic infection was associated with mortality rates varying between 20% and 45% among the flocks. Complete postmortem examination showed the presence of Cysticercus tenuicollis in internal organs such as the liver, lung, heart, and diaphragm of lambs. Examination of the feces of herding dogs showed the presence of eggs and gravid proglottids consistent with that of Taenia hydatigena. Praziquantel was used for the treatment of both infected lambs and herding dogs. Based on our findings, it was concluded that the main source of infection was the infected stray dogs. پرونده مقاله

سالینومایسین یک آنتی بیوتیک یونوفوره بوده که به طور گسترده در صنعت طیور برای کنترل و پیشگیری از کوکسیدیوز استفاده می شود. سمیت یونوفور احتمالاً به دلیل آسیب اکسیداتیو ناشی از تولید رادیکال های آزاد است. کورکومین جزء اصلی زردچوبه بوده که دارای طیف وسیعی از فعالیت آنتی اکسیدانی، ضد التهابی و ضد سرطانی است. هدف از این مطالعه بررسی اثر نانو کورکومین به عنوان یک آنتی اکسیدان طبیعی بر جوجه های گوشتی مسموم شده با دوز سمی سالینومایسین بود. در این مطالعه 60 قطعه جوجه گوشتی به طور تصادفی به 5 گروه تقسیم شدند. گروه اول به عنوان شاهد در نظر گرفته شد. گروه دوم سالینومایسین را با دوز 300 میلی گرم بر کیلوگرم وزن بدن، روزانه به مدت 14 روز دریافت کردند. گروه های 3، 4 و 5 علاوه بر سالینومایسین، به ترتیب روزانه 50، 100 و 200 میلی گرم بر کیلوگرم وزن بدن نانوکورکومین را به مدت 14 روز دریافت کردند. سپس، نمونه های خون و بافت برای ارزیابی بیوشیمیایی و هیستوپاتولوژی جمع آوری شد. مشاهده شد که نانوکورکومین بروز و شدت ضایعات هیستوپاتولوژیک کلیه را کاهش داده و به نظر می رسد که درمان با نانوکورکومین باعث بهبود وضعیت و کاهش تعداد سلول های التهابی می شود. همچنین پارامترهای هیستومورفومتری را به طور معنی داری بهبود بخشید (05/0>p). به نظر می رسد شرایط نامطلوب ناشی از مسمومیت با سالینومایسین با تجویز خوراکی نانوکورکومین قابل بهبود باشد. پرونده مقاله