Tooth extract is a chronic disease affecting a large number of people, especially children. Due to the high rate of tooth decay and the effect of nutrition and obesity on dental caries, this paper aims to investigate the relationship between body mass index (BMI) and dental caries (dmft) in children. This descriptive-analytical study was performed on a sample of 232 children age 6 to 9 years referred to Khorramabad Dental School in the academic year 2020-2021. The height, weight and BMI were measured for all children and their dmft score was determined based on the criteria of standards defined by the World Health Organization (WHO) and the data were analyzed using STATA 14 software. The obtained results showed that the mean age of students was 7.351±0.07 years, their BMI was 15.39 ± 2.81 and their dmft was 5.51 ± 2.8 are underweight, 26.29% are normal weight, 12.5% ​​are overweight and 6% are fat. Moreover, in this research molecular dynamics (MDs) simulation was used to predict the physical and mechanical properties of lithium disilicate as a restorative material. According to the experimental results, the mean dmft index in Khorramabad students is high and programs should be considered to control dental caries and reduce them. Regarding the relationship between dmft and BMI, contradictory results were obtained that due to the multifactorial nature of caries and obesity, the relationship between the two is complex and needs further investigation. The average density value of the simulated model of lithium disilicate is 2.551 at 300 K and 2.479 gr/cm3 at 450 K, which is very close to the real value of 2.6 ± 0.3 gr/cm3. The obtained results from the MDs showed that it is in good agreement with the experimental observation. پرونده مقاله

Today, great interest has been generated by dental science and engineering researchers to use bio-based nanoparticles to deliver therapeutic molecules such as drugs, genes, and tissue engineering. Controlling particle size, charge, surface morphology and release rate of loaded molecules is important for using nanoparticles based on biopolymers and bioactive ceramics such as tricalcium phosphates (TCP) as drug/gene carriers. Recently, drug release systems and nanoparticle systems have attracted much attention as suitable carriers. Drug delivery systems are methods used to ensure that drugs reach the required areas in the body. Natural polymers such as proteins have attracted a lot of attention due to their biocompatibility properties with living organisms. Among polymers, silk fibers have attracted the attention of researchers in the field of textiles and medicine due to their good properties such as low specific gravity, strength and high thermal resistance. In addition, their use as carriers of drugs, therapeutic genes and biomaterials for tissue engineering with applications in the field of dental and orthopedic materials has been reviewed. پرونده مقاله