Introduction: Traditional medicinal plants have gained increasing popularity in the last decades due to the natural origin, low price and fewer side effects. Herbal products are complex mixture of organic chemicals that may come from raw or processed part of plants.Studies have shown that lots of drugs have herbal bases.Over time, the effect of herbal medicines on the immune system has been paid lots of attention. Asteraceae or Compositae is an exceedingly large, annual and widespread family of flowering plants. They produce secondary metabolites, such as flavonoidsand terpenoids which have lots of effect on our body. Many of Asteraceaefamily are plants which have been used in traditional medicine.Many studies have shown the effect of Asteraceae family plants or their extract on immune-mediated diseases, especially their anti-inflammatory effect. Methods: In this article, we reviewed the medicinal properties of fivegenuses of Asteraceae family plants which influence the immune system. پرونده مقاله