Introduction: Studies have shown antibacterial activity of anise and on the other hand, Listeria monocytogenes, one Gram-positive pathogen is responsible for listeriosis. Thus, this study aimed to investigate the effect of subcutaneous administration of anise essential oil and oral administration of its aqueous extract and also comparison of their effects in BALB/c mice infected with listeriosis. Methods: Two units, by using insulin syringe, of Listeria monocytogenes prepared in 0.5 McFarland standard was intraperitoneally administrated to mice and agglutination test was done to ensure before anise administration. BALB/c mice (n=50) infected with listeriosis received anise aqueous extract (AAE) (5 g/100 g drink water) and 1-unit anise essential oil (AEO) by using insulin syringe was subcutaneously administrated to other mice (n=50) for 1 week. Other mice (n=24) were considered as control. Results: Results showed that AAE and AEO could improve mice contaminated with listeriosis, although mice treated with AAE were efficiently cured than those who received AEO (37 vs. 12). Conclusion: On the basis of the results, it can be recommended that the use of AAE for treatment of listeriosis is tenable. پرونده مقاله

Introduction: Antifungal drugs have major limitations such as fungal resistance to classical drugs and treatment costs. It has been reported that antifungal activity of some essential oils as safe combinations. Thus, the present study was conducted to investigate the antifungal activity of garlic, thyme, aloe vera and cinnamon essential oils against Candida albicans, Aspergillus flavus, Aspergillus niger and Mucor himalis. Methods: Antibacterial activities of essential oils were evaluated by disk diffusion assay. The data were collected for 1, 3, 7 and 10 days. Results: Findings indicated that all essential oils showed similar antifungal activity against A. flavus, A. niger and M. himalis. Garlic essential oil was more efficient against C. albicans compared with other essential oils. Conclusion: The selected essential oils can efficiently show antifungal activity against A. flavus, A. niger and M. himalis, but garlic essential oil showed antifungal activity against the selected fungus Thus, garlic essential oil can be suggested as helper for common antifungal drugs. پرونده مقاله