A carbon nanocomposite electrode has been designed by incorporation of montmorillonite nanoclay
into the carbon ionic liquid electrode for the electrochemical determination of amitriptiline . The surface of
the proposed electrode was characterized by scanning electron microscopy. The presence of ionic liquid as
a binder is believed to be responsible for the electrocatalytic activity of the proposed electrode for oxidation
of amitriptyline. Low detection limit of 24 nM for amitriptyline was achieved. High stability and reproducibility
as well as the ease of preparation, low cost and surface renewal made this electrode ideal for the
determination of amitriptyline in human body fluids. پرونده مقاله

We used an effective electrochemical sensor for the determination of imipramine at pH 7.2 using a carbon nanocomposite electrode. The electrode has been designed by incorporation of montmorillonite nanoclay into the carbon ionic liquid electrode. The high sensitivity of 1.714 μA (μM)-1, two linear calibration ranges of 0.1–2 μM and 2-40 μM, and detection limit of 19 nM were achieved. The relative standard deviations (RSDs) were 2.73% (n=7, 2 μM), 2.97% (n=4, 2 μM), respectively. Thus, this modified electrode was further applied to the determination of imipramine in urine sample. پرونده مقاله