Co3O4/NiO@GQDs@SO3H nanocomposite as high performance catalyst for the preparation of pyrimidines

محورهای موضوعی : Journal of Nanoanalysis

Hossein Shahbazi-Alavi ¹ , Ali Abbas ² , Javad Safaei-Ghomi ³

1 - Young Researchers and Elite Club, Kashan Branch, Islamic Azad University, Kashan, Iran, E-mail addresses: [e-mail] Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Iran
2 - College of Applied Medical Sciences, University of Kerbala, Iraq
3 - Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Iran

تاریخ دریافت : 1399/06/03 تاریخ پذیرش : 1399/06/03 تاریخ انتشار : 1398/12/11

کلید واژه: nanocomposite one, pot Heterogeneous catalysts pyrimidine nanoanalysis,

چکیده مقاله :

Co3O4/NiO@GQDs@SO3H nanocatalyst has been used as an effective catalystfor the preparation of 2,4-diamino-6-arylpyrimidine-5-carbonitrile derivativesthrough a three-component reaction of malononitrile, aromatic aldehydes andguanidine hydrochloride under reflux conditions in ethanol. The catalyst has beencharacterized by FT-IR, XRD, SEM, EDS, BET, TGA, XPS and VSM. Atom economy,reusable catalyst, low catalyst loading, applicability to a wide range of substratesand high yields of products are some of the notable features of this protocol.