Co3O4/NiO@GQDs@SO3H nanocomposite as high performance catalyst for the preparation of pyrimidines
الموضوعات : Journal of Nanoanalysis
Hossein Shahbazi-Alavi
1
(Young Researchers and Elite Club, Kashan Branch, Islamic Azad University, Kashan, Iran, E-mail addresses: hossien_shahbazi@yahoo.com
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Iran)
Ali Abbas
2
(College of Applied Medical Sciences, University of Kerbala, Iraq)
Javad Safaei-Ghomi
3
(Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Iran)
الکلمات المفتاحية: nanocomposite one, pot Heterogeneous catalysts pyrimidine nanoanalysis,
ملخص المقالة :
Co3O4/NiO@GQDs@SO3H nanocatalyst has been used as an effective catalystfor the preparation of 2,4-diamino-6-arylpyrimidine-5-carbonitrile derivativesthrough a three-component reaction of malononitrile, aromatic aldehydes andguanidine hydrochloride under reflux conditions in ethanol. The catalyst has beencharacterized by FT-IR, XRD, SEM, EDS, BET, TGA, XPS and VSM. Atom economy,reusable catalyst, low catalyst loading, applicability to a wide range of substratesand high yields of products are some of the notable features of this protocol.
