Convenient synthesis of tetrazolo[1,5-b]pyridazine derivatives
محورهای موضوعی : Journal of Chemical Reactivity and Synthesis
Maryam Manasir
1
(Department of Chemistry, Faculty of Sciences, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran)
Mohsen Nikpour
2
(Department of Chemistry, Faculty of Sciences, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran)
کلید واژه: Hydrazine, diazotization, 3, 6-dichloropyridazine, tetrazolo[1, 5-b]pyridazine,
چکیده مقاله :
Reaction of 3,6-dichloropyridazine with hydrazine gave 1-(6-chloropyridazin-3-yl) hydrazine in high yield in ethanol at room temperature. Diazotization of the latter compound converted it to 6-chlorotetrazolo[1,5-b]pyridazine quantitatively in ice bath. 6-Chlorotetrazolo[1,5-b]pyridazine underwent a chlorine substitution is ethanol with amines at room temperature.The reaction mechanism and spectral data is discussed.
