The Effect of Continuous and Interval aerobic Trainings on Body Mass Index and Serum Levels of ICAM-1 and VCAM-1 in Men with Heart Failure
محورهای موضوعی :
Report of Health Care
Ladan Hosseni Abrishami
1
,
Seyed Mahmoud Hejazi
2
,
Amir Rashidlamir
3
,
Rambod khajei
4
1 - Department of physical education, Khorasan e Razavi Sience and Research Branch, Islamic Azad University, Neyshabour, Iran.
2 - Department of physical education, Neyshabour Branch, Islamic Azad University, Neyshabour, Iran.
3 - Department of physical education, Neyshabour Branch, Islamic Azad University, Neyshabour, Iran.
4 - Department of physical education, Neyshabour Branch, Islamic Azad University, Neyshabour, Iran.
تاریخ دریافت : 1397/08/24
تاریخ پذیرش : 1398/03/10
تاریخ انتشار : 1398/02/11
کلید واژه:
Aerobic Training,
BMI,
ICAM-1,
VCAM-1,
Heart Failure,
چکیده مقاله :
Introduction: Adhesive molecules of cellular markers have been applied to identify the process of formation of atherosclerotic plaque of vascular endothelial wall. The present research aimed to evaluate the effect of continuous and interval aerobic trainings on body mass index and serum levels of ICAM-1 and VCAM-1 in men with heart failure. Methods: In the present research, 42 middle-aged men with heart failure were purposefully and randomly divided to three equal groups (each 14 participants) including continuous, periodic, and control aerobic exercises. Continuous exercise (with the intensity of 45-70% maximum heart rate) and periodic exercises (with the intensity of 45-80% of MHR) were done for 3 days a week, with a total term of 8 weeks. Before and after the implementation of the exercise plan, blood samples were taken from three groups. Data were analyzed by one-way ANOVA (P≤0.05). Results: Comparison of mean of intra-group indicated a significant decrease in the level of cellular adhesion molecule-1 and vascular adhesion molecules-1 and body mass index in the exercise groups (P≤0.05). In Intragroup comparison, the two groups of exercise, VCAM-1(P=0.0001) and body mass index (P=0.002) were significantly decreased, but no significant change was observed in ICAM-1(P=0.107). Decrease in VCAM-1 levels and BMI between the two exercise groups were more significant than the control group, but there was no significant difference between the two groups of periodic and aerobic. Conclusion: With decreasing BMI and VCAM-1 levels, aerobic exercises may have a significant role in the prevention and control of cardiovascular disease in patients with heart failure.
منابع و مأخذ:
von Haehling S, Doehner W, Anker SD. Nutrition, metabolism, and the complex pathophysiology of cachexia in chronic heart failure. Cardiovasc Res. 2007; 73 (2): 298- 309.
Dickstein K, Cohen Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole Wilson PA, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur J Heart Failure. 2008; 10 (10): 933- 989.
von Haehling S, Lainscak M, Springer J, Anker SD. Cardiac cachexia: a systematic overview. Pharmacol Ther. 2009; 121 (3): 227- 252.
Jankowska EA, Ponikowski P, Piepoli MF, Banasiak W, Anker SD, Poole-Wilson PA. Autonomic imbalance and immune activation in chronic heart failure - pathophysiological links. Cardiovasc Res. 2006; 70 (3): 434- 445.
Blake GJ, Ridker PM. Inflammatory bio-markers and cardiovascular risk prediction. J Intern Med. 2002; 252 (4): 283- 294.
Lira FS, Yamashita AS, Uchida MC, Zanchi NE, Gualano B, et al. Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile. Diabetology Metab Synd. 2010; 2: 31.
Hejazi SM, Hosseni Abrishami L. The effect of 8 week aerobic exercises on serum levels of cell adhesion molecules among middle-aged women. Adv Stud Biol. 2013; 5 (6): 279- 289.
Van Kimmenade RR, Januzzi JL. Emerging biomarkers in heart failure. Clin Chem. 2012; 58 (1): 127- 138.
Saxton J, Zwierska I, Hopkinson K, Espigares E, Choksy S, Nawaz S, et al. Effect of upper- and lower-limb exercise training on circulating soluble adhesion molecules, hs-CRP and stress proteins in patients with intermittent claudication. Eur J Vasc Endovasc Surg. 2008; 35 (5): 607- 613.
Malik I, Danesh J, Whincup P, Bhatia V, Papacosta O,Walker M, et al. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet. 2001; 358 (9286): 971- 976.
Signorelli SS, Mazzarino MC, Di Pino L, Malaponte G, Porto C, Pennisi G, et al. High circulating levels of cytokines (IL-6 and TNFalpha), adhesion molecules (VCAM-1 and ICAM-1) and selectins in patients with peripheral arterial disease at rest and after a treadmill test. Vasc Med. 2003; 8 (1): 15- 19.
Mathur N, Pedersen B.K. Exercise as a mean to control low-grade systemic inflammation. Mediators of Inflammation. Mediators Inflamm. 2008; 109502: 1- 6.
Mogharnasi M, Gaeini A, Javadi E, Kordi M, Ravasi A, Sheikholeslami Vatani D. The effect of endurance training on inflammatory biomarkers and lipid profiles in wistar rats. WJSS. 2009; 2 (2): 82- 89.
Adamopoulos S, Parissis J, Kroupis C, Georgiadis M, Karatzas D, Karavolias G, et al. Physical training reduces peripheral markers of inflammation in patients with chronic heart failure. Eur Heart J. 2001; 2: 791- 797.
Aksoy S, Findikoglu G, Ardic F, Rota S, Dursunoglo D. Effect of 10-week supervised moderate –intermittent vs. Continuous aerobic exercise programs on vascular adhesion molecules in patients with heart failure. Am J Phys Med Rehabil. 2015; 94 (10): 898- 911.
Sabatier MJ, Schwark EH, Lewis R, Sloan G, Cannon J, McCully K. Femoral artery remodeling after aerobic exercise training without weight loss in women. Dyn Med. 2008; 7 (1): 13- 14.
Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et. al. Physical activity and public health. A recommendation from the centers for disease control and prevention and the American College of Sports Medicine. JAMA. 1995; 273 (5): 402- 407.
Jakicic JM, Wing RR, Butler BA, Robertson RJ. Prescribing exercise in multiple short bouts versus one continuous bout: effects on adherence, cardiorespiratory fitness, and weight loss in overweight women. Int J Obes Relat Metab Disord. 1995; 19 (12): 893- 901.
Friedenreich CM, O'Reilly R, Shaw E, Stanczyk FZ, Yasui Y, Brenner DR, et al. Inflammatory marker changes in postmenopausal women after a year-long exercise intervention comparing high versus moderate volumes. Cancer Prev Res. 2016; 9 (2): 196- 203.
AACVPR. Cardiac rehabilitation resource manual. Chicago, IL. Human Kinetics, 2006; 142-147.
Carbone S, Canada JM, Buckley LF, Trankle CR, Dixon DL, Buzzetti R, et al. Obesity contributes to exercise intolerance in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2016; 68 (22): 2487- 2488.
Fatouros I, Tournis S, Leontsini D, Jamurtas A, Sxina M, Thomakos P, et al. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. J Clin Endocrinol Metab. 2005; 90 (11): 5970- 5977.
Behboudi L, Izadi M. The effect of six weeks aerobic training on body composition and serum level of IL-10 in middle- aged obese females. Iranian J Obs Gyn Infer. 2017; 20 (80): 51- 60.
Mehdizadeh R, Khosravi A. Comparison of effects of aerobic with low intensity resistance trainings on indices of anthropometric adiposity in overweight women. Sport Physiol Manag Inves. 2016; 7 (4): 33- 43.
Lee JS, Kim CG, Seo TB, Kim HG, Yoon SG. Effects of 8-week combined training on body composition, isokinetic strength, and cardiovascular disease risk factors in older women. Aging Clin Exp Res. 2015; 27 (2): 179- 186.
Yosefi A, Abedi B, Sayyah M. Effect of eight weeks of aerobic training with moqlenjan supplementation on lipid profile and glycemic indices of overweight men. Rep Health Care. 2017; 3 (3): 71- 80.
Esmaili Alamdari M, Fathi M, Bije N, Pouryamehr E. The effect of eight weeks of aerobic exercise on interleukin-6, insulin resistance and blood glucose of overweight female. Rep Health Care. 2016; 2 (3): 53- 61.
Rabei SZ, Mohsen Salesi M. The effect of 8 weeks aerobic exercise training on cardiovascular risk factors in men with type 2 diabetes mellitus. Rep Health Care. 2015; 1 (3): 99- 103.
Pearson MJ, Mungovan SF, Smart NA. Effect of aerobic and resistance training on inflammatory markers in heart failure patients: systematic review and meta-analysis. Heart Failure Rev. 2018; 23 (2): 209– 223.
Ranković G, Miličić B, Savić T, Đinđić B, Mančev Z, Pešić G. Effects of physical exercise on inflammatory parameters and risk for repeated acute coronary syndrome in patients with ischemic heart disease. Vojnosanit Pregl. 2009; 66 (1): 44- 48.
Haghir H, Hejazi S M, Minaee S. Changes of serum intercellular adhesion molecule – 1, vascular adhesion molecule-1 and C- reactive protein in middle-aged men with heart failure after eight weeks of aerobic exercise. JSSU. 2017; 24 (12): 1- 8.
Ribeiro F, Alves A.J, Teixeira M, Miranda F, Azevedo C, Duarte J.A and et al. Exercise training increases interleukin-10 after an acute myocardial infarction: a randomised clinical trial. Int J Sports Med. 2012; 33 (3): 192- 198.
Keating SE, Machan EA, O'Connor HT ,Gerofi JA, Sainsbury A, Caterson ID, et al. Continuous exercise but not high intensity interval training improves fat distribution in overweight adults. J Obes. 2014; 834865.
Higashi Y, Yoshizumi M. Exercise and endothelial function: role of endothelium-derived nitric oxide and oxidative stress in healthy subjects and hypertensive patients. Pharmacol Ther. 2004; 102 (1): 87- 96.
Ribeiro F, Alves AJ, Duarte JA, Oliveira J. Is exercise training an effective therapy targeting endothelial dysfunction and vascular wall inflammation?. Int J Cardiol. 2010; 141 (3): 214- 221.