Evaluation of the prevalence of Systolic hypertension in Persian cats with poly cystic kidney disease
محورهای موضوعی : بیماریهای داخلی دامهای کوچک
Niloufar Saberi
1
,
Ehsan Khaksar
2
,
Mohammad Molazem
3
,
Siamak Mashhadi Rafiee
4
1 - Department of Clinical Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 - Department of Clinical Sciences, Garmsar Branch, Islamic Azad University, Garmsar, Iran
3 - Department of Veterinary Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran
4 - Department of Clinical Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
کلید واژه: Persian cats, Polycystic kidney disease, Systolic hypertension, Prevalence, Doppler Ultrasonography ,
چکیده مقاله :
Polycystic kidney disease (PKD) is a genetic disorder prevalent in Persian and Persian-related cat breeds. It often leads to systemic arterial hypertension, which can severely affect the kidneys and heart if not managed. This study aimed to assess the prevalence of hypertension in Persian cats with PKD. Conducted at Tehran Azma Veterinary Center from March to May 2023, the research included 24 cats of Persian or Persian-mixed breeds. The cats were divided into two groups based on kidney ultrasonography examinations: a control group and a PKD group, each containing 12 cats. Systolic blood pressure was measured using Doppler ultrasonography and categorized according to the guidelines of the International Renal Interest Society (IRIS). The mean kidney size in cats with PKD was found to be significantly larger than that in the control group (p< 0.05). The average blood pressure of the PKD cats was substantially higher, recorded at 165.0 ± 23.5 mm Hg, with a higher mean in azotemic cats. The study found that 75% of the PKD cats had hypertension, with 25% experiencing severe hypertension, putting them at a high risk of future organ failure. In conclusion, hypertension is highly prevalent in Persian cats with PKD, and the progression of PKD, along with the presence of azotemia, can impact systolic blood pressure. Therefore, proactive strategies and hypertension management should be considered in PKD cats.
Polycystic kidney disease (PKD) is a genetic disorder prevalent in Persian and Persian-related cat breeds. It often leads to systemic arterial hypertension, which can severely affect the kidneys and heart if not managed. This study aimed to assess the prevalence of hypertension in Persian cats with PKD. Conducted at Tehran Azma Veterinary Center from March to May 2023, the research included 24 cats of Persian or Persian-mixed breeds. The cats were divided into two groups based on kidney ultrasonography examinations: a control group and a PKD group, each containing 12 cats. Systolic blood pressure was measured using Doppler ultrasonography and categorized according to the guidelines of the International Renal Interest Society (IRIS). The mean kidney size in cats with PKD was found to be significantly larger than that in the control group (p< 0.05). The average blood pressure of the PKD cats was substantially higher, recorded at 165.0 ± 23.5 mm Hg, with a higher mean in azotemic cats. The study found that 75% of the PKD cats had hypertension, with 25% experiencing severe hypertension, putting them at a high risk of future organ failure. In conclusion, hypertension is highly prevalent in Persian cats with PKD, and the progression of PKD, along with the presence of azotemia, can impact systolic blood pressure. Therefore, proactive strategies and hypertension management should be considered in PKD cats.
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