The Most Important Pharmaceutical Benefits of Sulforaphane, a Sulfur-Rich Compound in Cruciferous

محورهای موضوعی : Research On Crop Ecophysiology

WENLI SUN ¹ , Mohamad Hesam Shahrajabian ² , HONG SHEN ³ , MEHDI KHOSHKHARAM ⁴ , QI CHENG ⁵

1 - -Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
2 - Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaSenior Researcher- Faculty of Agriculture- Islamic Azad University, Isfahan (Khorasgan) Branch, Isfahan, Iran
3 - College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, Zhejiang, China
4 - Faculty of Agriculture, Islamic Azad University, Isfahan (Khorasgan) Branch, Isfahan, Iran
5 - 1-Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China 4-College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, 071000, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, Baoding, Hebei 071000, China

تاریخ دریافت : 1399/09/22 تاریخ پذیرش : 1399/09/22 تاریخ انتشار : 1398/03/11

کلید واژه: cancer, Health Benefits, Keywords: Natural Compounds, Sulforaphane,

چکیده مقاله :

The Most Important Pharmaceutical Benefits of Sulforaphane, a Sulfur-Rich Compound in Cruciferous Mohamad Hesam Shahrajabian1,2, Wenli Sun1, and Qi Cheng1,2* 1-Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China 2-College of Life Sciences, Hebei Agricultural University, Baoding, Hebei, 071000, China; Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, Baoding, Hebei 071000, China. *Corresponding author E-mail: [e-mail]; [e-mail] Received: 10 March 2019 Accepted: 20 June 2019 Abstract Natural products have played a key role in drug discovery and development in modern days. Sulforaphane can be found in a wide variety of cruciferous vegetables, including cabbage, Brussels sprouts, cauliflower, broccoli, Chinese broccoli, broccoli sprouts, broccoli raab, Kohlrabi, collards, kohlrabi, mustard, turnip, kale and radish. The most important health benefits of sulforaphane is its effects again breast cancer, lung cancer cells, human liver cancer cells, gastric cancer cell lines, ovarian cancer, prostate cancer, pancreatic cancer, colon cells cancer, treatment of cancer cell senescence, anti-inflammatory properties, antineoplastic agent, reduction of placental and endothelial oxidative stress, potential in mixed granulocyte asthma, treatment of various neurological disorders, protection again skeletal muscle disease, anti-allergic and its impact against oxidative stress. Keywords: Natural Compounds, Sulforaphane, Health Benefits, Cancer.