List of Articles spleen

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  1 - Effect Ofsilver nanoparticle injection on body weight, liver index and spleen index in rat
  Hossein Hamzehei Hamed Alizadeh Nader Hajizadeh Mohammad Taghi Moazed
  Inroduction and Objective:Silver nanoparticles may be toxic. The mechanism of toxicity is not known. Great concern for the health of humans in nature has created. The changes in body weight, liver index and spleen index can be effective in identifying harmful factor in More

  Inroduction and Objective:Silver nanoparticles may be toxic. The mechanism of toxicity is not known. Great concern for the health of humans in nature has created. The changes in body weight, liver index and spleen index can be effective in identifying harmful factor in the body. This study was performed to examine the effects of silver nanoparticles on body weight and liver and spleen index in rats.Materials and Methods:21 adult female rats were randomly divided into 7 groups. The mice were weighed. Group 1 was sham. Control group 2 and group 3 to 7 experimental groups were treated respectively with 5, 10, 20, 40 and 80 ppm of silver nanoparticles. Mice treated for 10 days. On the eleventh day the rats were killed by diethyl ether anesthesia. The mice were weighed and then dissected; the liver and spleen were removed. Liver and spleen were weighed in order to calculate their index.Results:The results showed no significant change in body weight of mice, spleen weight, liver weight and liver index and spleen index.Conclusion:Intraperitoneal injection of silver nanoparticles does not affect the index in rat liver and spleen. Manuscript profile
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  2 - Study Of Morpholineand Physiological Saline Effect on Blood Parameters and Spleen Tissue Of NMRI Albino Male Mice
  Nasim Naiemi Hamid Reza Adeli Kobra Zare
  Inroduction and Objective: Morpholine is a substance with various applications in industry and agriculture which toxic effects can be absorbed into the body by ingestion, by inhalation and through skin. The present study aimed to study of morpholineand  physiological sa More

  Inroduction and Objective: Morpholine is a substance with various applications in industry and agriculture which toxic effects can be absorbed into the body by ingestion, by inhalation and through skin. The present study aimed to study of morpholineand  physiological saline effect on blood parameters and spleen tissue of6-week-old nmri albino male mice Materials and Methods: 40 adult male mice were placed in 4 experimental groups including control group, physiological saline (sham) group, treatment group A, fed with 300 mg/kg per day for 15 days, 1 ml of the prepared solution (0.009 ml morpholine+ 0.91 ml of distilled water) and group B, treated using the same method with the same volume of morpholine and physiological saline in the same period of time. After weighing, anesthesia and blood sampling, the number of red blood cells, hematocrit and hemoglobin were respectively measured using Neubauer slide, hematocrit capillary tube, and Sally method applying a plasma density refractometer. Microscopic and structural studies were conducted on prepared slides of spleen and statistical analyses were performed using SPSS19 software. Results: Increased number of red blood cells (%6.7), hematocrit (%21), plasma density (%25), and hemoglobin (%10) and decreased thickness of splenic capsule wall and becoming more fibrous (%8.3), increased thickness of central arteriole wall of white pulp (%30), increased spleen weight (%6.14), and reduced body weight (%2.14) were observed in group A, compared to control group and sham group. Considering group B, all listed features (except thickness of splenic capsule wall and weight loss) decreased. The results indicated a significant difference between group A and B (pConclusion: The significance of this relationship indicated that morpholine increased blood parameters, caused parenchyma adhesion, led to inflammation and increased spleen weight and decreased body weight and that physiological saline decreased its adverse effects. Given destructive effects of morpholine and its usage in our daily life, industry should look for a suitable replacement in order to maintain human health.    Manuscript profile
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  3 - Study of Changes Histomorphometry Spleen in Rats with Pregnancy and Lactation
  elham Etemadi Akbar Karimi Ali Asghar Pilevarian
  Inroduction & Objective: Major changes occurred in the mother's body during pregnancy, sometimes these changes for both mother and fetus at risk by recognizing the changes in the conditions of a woman's pregnancy can be managed. In this study, histomorphometry changes o More

  Inroduction & Objective: Major changes occurred in the mother's body during pregnancy, sometimes these changes for both mother and fetus at risk by recognizing the changes in the conditions of a woman's pregnancy can be managed. In this study, histomorphometry changes of spleen tissue during pregnancy and lactation in female Wistar rats were studied.Materials and Methods:In this study, 54 Wistar rats (12 male and 42 female) with an average weight of 220-240 g and after breeding and observation of vaginal plug 18 pregnant rats into  3 groups of 6 rats and 6 Rat non-pregnant adult female as control groups, and including the first day of pregnancy into 4 groups, control, 10 and 20 of pregnancy and the first week of lactation were divided. Then the rats were dissected and spleen tissue for histopathological examination with hematoxylin-eosin out and were. In cases the number of macrophages, white pulp megakaryocytes and diameter were evaluated. Statistical analysis ANOVA and Duncan test were examined. Results:The results indicated that in spleen tissue number of macrophages at 10 and 20 and diameter(P ConclusionProcesses of pregnancy increases changes done in  spleen tissue included   increases  white pulp and macrophages. These changes are dependent on mother's immune system Manuscript profile
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  4 - Histomorphology of spleen, liver, and pancreas of Calandra Lark
  Mehrdad Molai Jalil Pourhaji Motab
  Spleen, liver and pancreas are important in mammals and birds respectively because of the largest organ of lymphatic system, body's largest gland and digestive secretions. The aim of this study was to investigate structural features of the above organs in Calandra Lark. More

  Spleen, liver and pancreas are important in mammals and birds respectively because of the largest organ of lymphatic system, body's largest gland and digestive secretions. The aim of this study was to investigate structural features of the above organs in Calandra Lark. Twenty male and female Calandra larks were randomly selected and their liver, pancreas, and spleen were studied morphologically Subsequently, tissue samples of three males and three females were obtained and samples were stained using hematoxylin and eosin method. Liver has two lobes in all Calandra Larks, including right lobe and left one. Posterior edge of left lobe is lack of incision and isn’t divided into two pieces. The spleen is in the form of straightforward to curved bar in brown-red colour and is located in posterior part of the visceral surface of left lobe of liver. Pancreas is a long organ which is located between ascending and descending arms of duodenum and it is composed of two lobes. Gleason capsule doesn’t penetrate into liver's parenchyma; hence, lobule of tissue is unknown. A connective muscle capsule surrounds spleen, but trabeculae branches of it don't penetrate into the parenchyma. Outside of parenchyma, a very delicate capsule of loose connective tissue covers pancreas. Very delicate and short blades of the capsule are penetrated into the gland and it is divided into lobules. The results indicate that liver, spleen, and pancreas of Calandra lark have many similarities to Fringillidae, particularly Turdus merula Manuscript profile
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  5 - Study of the infestation rate of the kidney and spleen of domestic ruminants by Linguatula serrata nymphs in Urmia slaughterhouse
  سهراب Rasouli بهادر Hajimohammadi S.S Athari رضا Asadi مهران Mojarrad
       In this study, the prevalence of Linguatula serrata nymphs in kidneys and spleens of 800 domestic ruminants (cattle, buffalo, sheep and goat) in different sexes, ages and seasons was investigated. First, the kidneys and spleens were examined macrosco More

       In this study, the prevalence of Linguatula serrata nymphs in kidneys and spleens of 800 domestic ruminants (cattle, buffalo, sheep and goat) in different sexes, ages and seasons was investigated. First, the kidneys and spleens were examined macroscopically. Then, a digestion method was also applied. Infestation rate in the spleen of cattle, buffalo, sheep and goat were %0/5, %0, %0/5 and %1/5 respectively. No infestation was found in the kidneys. The results of this study shows that the infestation of domestic ruminants to Linguatula serrat nymphs in different sexes and ages were not significant. Also the infestation rate in different seasons was not significant. Manuscript profile
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  6 - Pathologic changes of the spleen in cattle slaughtered in Urmia abattoir
  Hadi Razeghi-fam Amir Amniattalab Abdullah Araghi-sooreh
  In the current study, 490 cattle (293 female and 197 male) were inspected at Urmia abattoir. In these inspections, 17 cattle (3.4%) had splenic lesions and that of these, 6 animals had some lesions in other organs in addition to the spleen. Tissue sampling from abnormal More

  In the current study, 490 cattle (293 female and 197 male) were inspected at Urmia abattoir. In these inspections, 17 cattle (3.4%) had splenic lesions and that of these, 6 animals had some lesions in other organs in addition to the spleen. Tissue sampling from abnormal spleens was performed. After tissue fixation, sections with 6 μ in thickness were prepared and stained by hematoxylin and eosin method. In the macroscopic inspection lesions such as splenomegaly, change of tissue consistency, color change and cyst had more abundance compared to other lesions. In the microscopic pathological evaluations, hemosiderosis, parenchymal fibrosis, tumor, necrosis, hemorrhage and focal necrosis areas were found in damaged spleens. In statistical analysis, color changes of the spleen between breed groups and consistency change of the spleen between sex groups showed significant difference (p<0.05). Indeed, abundance of injured spleens had a significant relation with age and sex of slaughtered cattle (p<0.05). Manuscript profile
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  7 - Effect of oral tramadol on rat Spleen tissue in male Wistar rats
  sahar molzemi mohsen aminian Mohammad Afshar Ardalan Amir Hossein Ashnaei
  10.30495/jdb.2021.682710
  Introduction : Tramadol the right drugs are synthetic opioid analgesics or Epoxied. The aim of this study was to evaluate the effect of oral tramadol on Spleen in rats Wistar male rats.Methods: In this study, 60 male Wistar rats randomized into 3 groups (1 control group More

  Introduction : Tramadol the right drugs are synthetic opioid analgesics or Epoxied. The aim of this study was to evaluate the effect of oral tramadol on Spleen in rats Wistar male rats.Methods: In this study, 60 male Wistar rats randomized into 3 groups (1 control group, and experimental groups of 1, 2). In control group adequate serum physiology and in experimental groups a dose of mercuric chloride infused into peritoneal cavity, for 30 days. The amount of gavage tramadol were, 50ml /kg group 2, 100 ml /kg , every other day for 30 days. After the end of the day appointed for Histological analysis Some blood parameters of Spleen samples, were tested.Results :And & two experimental groups a very high density and exposure area is full of blood and lymphoid cells. Particles of hemosiderin in both groups showed a significant increase..Conclusion: This study showed that long-term oral administration of Tramadol causes histological changes in the SpleenKeywords: tramadol, Spleen, mouse, rats, Wistar Manuscript profile
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  8 - Investigation of Deposition Amount of Zinc Oxide Nanoparticles with Various Doses in Spleen of Female Mice
  R. Kasra A. Shiravi V. Hojati
  Due to the increasing production of ZnO nanoparticles and their useful applications in biological systems, fewer studies have been performed about the side effects of these substances on the organism's body. To this end, in this study, we have investigated the depositio More

  Due to the increasing production of ZnO nanoparticles and their useful applications in biological systems, fewer studies have been performed about the side effects of these substances on the organism's body. To this end, in this study, we have investigated the deposition amount of zinc oxide nanoparticles on spleen of Syrian female NMRI mice. In this experimental study, 20 heads of female NMRI mice have been studied in the experimental and control groups. ZnO nanoparticles at concentrations of 100 and 300 mg per kg fed in the drinking water for 28 days, and after 28 days the mice were sacrificed, spleen tissue was removed and solved in the acid, and then the amount of deposited zinc oxide in the tissues was measured by atomic absorption spectrophotometry. According to the obtained results, it is observed that there are significant differences between the consumer groups (of ZnO nanoparticles) and control group. Deposition of Zinc oxide nanoparticles which was studied in the drinking water for 28 days in the mentioned experimental groups has had significant effects on the spleen. Manuscript profile
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  9 - Comparison of Morphometric and Histological Parameters of Spleen in Balb/c and C57BL/6 Strains of Mice Raised in the Same Conditions
  Morteza Abbaspour Samad Farashi Bonab
  10.22034/ascij.2023.1987261.1495
  Spleen is the largest lymphatic organ of the body and plays a role in blood purification, storage of red blood cells, removal of damaged old red blood cells and creation of specific immune responses. Some studies have shown that the spleen tissue has differences in some More

  Spleen is the largest lymphatic organ of the body and plays a role in blood purification, storage of red blood cells, removal of damaged old red blood cells and creation of specific immune responses. Some studies have shown that the spleen tissue has differences in some species. Since Balb/c and C57BL/6 bi-strain mice are chosen as the first choice in many biological researches, it is necessary to carefully evaluate the anatomical, histological and genetic differences between them in order to develop study models be chosen correctly. Therefore, the present study was conducted with the aim of investigating the morphometric and histological characteristics of spleen tissue in Balb/c and C57BL/6 mice. 10 Balb/c female mice and 10 C57BL/6 female mice were bred in the animal house under the same conditions. Then the spleen of mice was examined in terms of morphometric and histological characteristics. The data obtained from two groups were analyzed with t-set method and p < 0.05 was considered significant. The results showed that the shape and color of the spleen in mice do not differ significantly. The average spleen weight in Balb/c mice was slightly higher than that of C57BL/6 mice, which was not statistically significant. In the slides prepared from the spleen tissue of Balb/c and C57BL/6 mice, no visible difference was detected between the mice's spleen in terms of histology. Manuscript profile
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  10 - The Function of Eloquence Spleens in Educational Message in the Leili and Majnoon from Nezami
  naser naseri
  Abstract &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hakim Nezami, the poet of the 6th century, by his profound and strict knowledge of the vicissitudes of his era and familiarity with the kings and vassals' manner, considers himself as a social peacemaker, responsible to guide all More

  Abstract &nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hakim Nezami, the poet of the 6th century, by his profound and strict knowledge of the vicissitudes of his era and familiarity with the kings and vassals' manner, considers himself as a social peacemaker, responsible to guide all people, from the rulers to the peasants towards the good deed to provide ideal society regarding the mundane world and the dooms' day. To attain this, he provides a concoction of divine knowledge, religious problems, justice and altruism to cure and eradicate the disease and disorganization&nbsp; of the society. Though in his writings, Nezami has dealt with the Gnostic themes, love and historic and epic poems, the theme of all of them is didactic and ethical notes to the rulers and the ranks of people. I have tried to expound the educational and ethical aspects of the Leili and Majnoon from the rhetoric point of view and by using guidance, persuasion, threatening, irony, praying, and supplication. Altogether, Nezami's emphasis lies on guidance, prohibition of the roguery of the society. Manuscript profile
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  11 - Field study of monochromatic light effect on Bursal Body Weight ratio and spleen weight
  S.M. Pahlavani A. Sadrzadeh S. Mohamadi
  Lighting is a critical parameter in poultry breeding controlling many behavioral and physiological functions effectively. Measuring bursa of fabricius as the most important lymph node of the birds and setting the ratio of the bursa weight to the total body weight are al More

  Lighting is a critical parameter in poultry breeding controlling many behavioral and physiological functions effectively. Measuring bursa of fabricius as the most important lymph node of the birds and setting the ratio of the bursa weight to the total body weight are also important parameters to assess the health and functionality of the immune system. To do so, 34700 day-old chicks were selected from a 26-week Ross 308 breeder farm randomly. The chicks were free from congenital mycoplasma and salmonella infections. They were divided into three groups according to the capacity of the poultry house randomly. The only difference among the groups was the lighting wavelengths. On days 1, 24 and 46; 10 chicks were weighed in gram and euthanized each time; following the bursa of fabricius and spleen was weighed separately in 0.001 g to make the ratio of it with the total body weight. In case of measuring the spleen, there was no significant difference between the green and yellow lights in day 24 but both were less than the blue one while in day 46, there were no significant differences (P&gt;0/05) among the groups. In day 24, the weight of bursa of fabricius was not significantly different between the yellow and green lights but both were more than the blue light; also, it was true for the ratio of bursa of fabricius weight to the total body weight. In day 46, the analyses indicated that there were no significant differences (p&gt;0.05) in the ratio among the groups but the total body weight of the chicks breeding in blue light was a little more than the green one. Manuscript profile