List of Articles ovarian follicles

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  1 - The Effect Of Ethanol Extracts Of Hops on Sexual Hormone Levels and Ovarian Follicles Numbers in Syrian Adult Mice
  سید ابراهیم حسینی مهرداد شریعتی هادی توکلی
  Inroduction and ObjectiveThe use of chemical drugs to treat disease associated with usually side effects. In recent years the use of herbal medicines, which have far fewer side effects, in the treatment of various diseases, including infertility has increased. Therefore More

  Inroduction and ObjectiveThe use of chemical drugs to treat disease associated with usually side effects. In recent years the use of herbal medicines, which have far fewer side effects, in the treatment of various diseases, including infertility has increased. Therefore, this study aimed to evaluate the effect of hops flower extract on adult female sexual hormones and sexual dynastic cells.Materials and Methods:The experimental study was conducted on 40 adult female mice . The mice were divided into 5 groups of 8 including control groups (no treatment), the control (saline) and three experimental groups receiving doses of hops flower extract 50,100 and 150 mg /kg, respectively. All the prescription was done in gavage and in 21 days. At the end of the experiments, phlebotomizing the hearts of the animals was performed and by the isolating the serum was analyzed the sexual hormones levels and also by isolating ovaries, the primary, secondary and enteral follicles was accounted, and the results was analyzed by the ANOVA and tukey’s tests.Results:The results showed that the hops flower extract caused a significant increase in the hormones levels of estrogen, progesterone, and increasing the numbers of primary secondary and enteral follicles.Conclusion: Hops extract, probably by stimulating the secretion of hormones and with steroidal, flavonoids compounds, caused to increase the sexual hormones and the ovarian follicles Manuscript profile
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  2 - Effect of Feeding Quickly Degradable Nitrogen on the Development of Ovarian Follicles in Lactating Dairy Cows
  پ.م. داوودا ر. اسکاراموزی د.سی واتس
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  3 - نقش اپی‌نفرین و بروموکریپتین در مرغ‌های تخمگذار اثر اپی‌نفرین و بروموکریپتین بر رشد فولیکولی تخمدان و صفات تولیدی مرغ‌های تخمگذار
  ی. بدخشان م. مظهری
  این آزمایش برای مطالعه اثراپی‌نفرین و بروموکریپتین بر رشد فولیکولی تخمدان و صفات تولیدی مرغ‌های تخمگذار طراحی شد. 30 مرغ تخمگذار لگهورن در سن 50 هفتگی به طور مساوی بین سه تیمار (10 مرغ برای هر تیمار) شامل کنترل (5/0 میلی‌لیتر سرم فیزیولوژیکی به ازای هر مرغ در هفته)، اپی More

  این آزمایش برای مطالعه اثراپی‌نفرین و بروموکریپتین بر رشد فولیکولی تخمدان و صفات تولیدی مرغ‌های تخمگذار طراحی شد. 30 مرغ تخمگذار لگهورن در سن 50 هفتگی به طور مساوی بین سه تیمار (10 مرغ برای هر تیمار) شامل کنترل (5/0 میلی‌لیتر سرم فیزیولوژیکی به ازای هر مرغ در هفته)، اپی‌نفرین (5/0 میلی‌لیتر به ازای هر مرغ در هفته) و بروموکریپتین (100 گرم به ازای هر کیلوگرم وزن بدن) تقسیم شدند. تزریق تیمارها به صورت یکبار در هفته و به مدت 10 هفته انجام شد. در انتهای دوره آزمایش همه مرغ‌ها کشته شده و تخمدان، مجرای تخم و فولیکول‌ها مورد ارزیابی قرارگرفت. رشد فولیکول‌ها به طور معنی‌داری تحت تأثیر تزریق اپی‌نفرین و بروموکریپتین قرار گرفت (01/0>P). تعداد فولیکول‌های بزرگ وکوچک زرد رنگ و فولیکول‌های بزرگ سفید رنگ تخمدان در مرغ‌های تزریق شده با اپی‌نفرین و بروموکریپتین بیشتر از مرغ‌های گروه کنترل بود (01/0>P). تزریق اپی‌نفرین و بروموکریپتین منجر به کوتاه شدن روزهای توقف تخمگذاری در مقایسه با گروه کنترل گردید (01/0>P). میانگین تولید تخم مرغ هفتگی و درصد تولید تخم مرغ در مرغ‌های تزریق شده با اپی‌نفرین و بروموکریپتین بیشتر از مرغ‌های گروه کنترل بود (01/0>P). نتایج آزمایش نشان داد که اپی‌نفرین و بروموکریپتین می‌توانند منجر به رشد و توسعه فولیکول‌ها و تحریک تخمگذاری در انتهای دوره تولیدی مرغ‌های تخمگذار گردند. Manuscript profile
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  4 - Evaluation of the protective effect of Nigella sativa oil on ovarian follicles in mice treated with silver nanoparticles
  SMA shariatzadeh Mozhgan Khagavi Jafarabad
  Aim: the effect of Nigella sativa oil (NSO) as an efficient antioxidant on ovarian follicles following treatment with Silver Nanoparticles (SNP) in adult mice. Material and methods: Twenty-four adult NMRI mice, weighing 27-30g were used in the present experiment. The an More

  Aim: the effect of Nigella sativa oil (NSO) as an efficient antioxidant on ovarian follicles following treatment with Silver Nanoparticles (SNP) in adult mice. Material and methods: Twenty-four adult NMRI mice, weighing 27-30g were used in the present experiment. The animals were kept under optimum conditions of temperature (At 21± 2 ° C and ambient lighting conditions 12 hours of darkness and 12 hours of light) humidity and maintained on standard pellet diet with adequate water. They were divided into four groups of (six mice per group): control; Silver Nanoparticles (300 mg/kg/day, orally), Nigella sativa oil (5 ml/kg/day, orally) and finally Silver Nanoparticles plus Nigella sativa oil. After 30 days, the mice were sacrificed and the ovary tissues were separated. The results were analyzed using one-way ANOVA and Tukey’s test, and the means were significantly different at P<0.05. Results: The results of this study showed that, the mean total volume of ovary and the number of primordial, primary, secondary and graph follicles significantly decreased in the Silver Nanoparticles group compared with the control group (p<0.05). Nigella sativa oil significantly increased the above parameters in the SNP +NSO group compared to silver nanoparticles group (p<0.05). Furthermore, the number of follicles and total volume of ovary significantly increased in the Nigella sativa oil treated mice compared to the control ones (p<0.05) (Table 1). Conclusion: So it is not far-fetched that this oil has improved the factors in our study. Manuscript profile
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  5 - Investigation the effect of carboplatin on oogenesis and uterus changes in adult female NMRI mice strain
  Sepideh Gholami Yarahmadi nasim HAYATI ROODBARI KAZEM PARIVAR Gholamhassan Vaezi
  Cancer is one of the most common diseases around the world. The most important therapies for cancer are chemotherapy that is performed by various medications. One of the common drugs in chemotherapy is “Carboplatin”. In this study, the effects of Carboplatin More

  Cancer is one of the most common diseases around the world. The most important therapies for cancer are chemotherapy that is performed by various medications. One of the common drugs in chemotherapy is “Carboplatin”. In this study, the effects of Carboplatin on oogenesis and uterine changes in NMRI mouse strain have been investigated In vivo. In this study, 30 adult female mice were randomly divided into five groups: control, sham and three experimental groups. Experimental groups were injected Carboplatin with 0.36, 0.18, 0.09 mg/ml density for 28 days and all were injected subcutaneously. After describing the animals, the ovary and uterus were separated and subjected to histopathologic and stained by hematoxylin and eosin. Blood sampling was performed to study both estradiol and FSH. The results were analyzed using one-way ANOVA and SPSS software. By using Carboplatin,, the number of primordial, secondary, Graafian follicles, corpus lutea and blood vessels decreased and the number of atretic follicles increased. The diameter of ovary in experimental groups decreased, but there was no significant change in diameters of follicles. Uterine studies showed that, the uterine’ diameter and layers, and the diameter of lumen reduced. In addition, the number of uterine glands decreased. Also, the levels of FSH and estradiol decreased. Regarding to using Carboplatin, this drug by decrease in the number of primordial, secondary and Graafian follicles, increase in number of atretic follicles, and also disruption of the hormonal system, the probability of premature aging may increase and has a negative effect on fertility. Manuscript profile