• List of Articles liver tissue

      • Open Access Article

        1 - Effect of dietary supplementation vitamin C in liver tissue destruction rainbow trout (Oncorhynchus mykiss) in the face of nano-zinc oxide
        Darabitabar, F., Hedayati, A., salati, A., Hosseinifar, H. .
        Unsuitable water quality and pollutants in the water causing stress response and eventually occurs on physiological parameters of fish health and reduced immune function of fish, hence the use of vitamins seems like a very necessary safety supplier for improve immunity. More
        Unsuitable water quality and pollutants in the water causing stress response and eventually occurs on physiological parameters of fish health and reduced immune function of fish, hence the use of vitamins seems like a very necessary safety supplier for improve immunity. 170 pieces of fish with an average weight of 170 grams was taken at 70 L tanks. Then fish were placed in 40 and 80 mg per liter concentrations of nanoparticles on two levels of vitamin C (400 and 800 mg per kilogram of food). Compatibility during was performed twice feeding during this period fish with commercial food were fed at a rate of 2% body weight per day. The water used in the workshop physicochemical factors including temperature C ° 20 ± 2, pH 7/2 ± 0/4 and dissolved oxygen 6/74 ± 0/2 and water hardness 185 ± 16 ppm was measured on a daily basis and fixed in all treatments were considered. The combination of 800 mg/kg of vitamin C and 40 mg/l of Nano simultaneously taking the cause of the protective effect of vitamin C by Nano zinc on liver damage so that damages were lower compared with other treatments. This study shows that the use of a suitable material such as vitamin C at high concentration, 800 mg per kg in the diet of rainbow trout, seems to be necessary and useful for increasing the antioxidant defense. Manuscript profile
      • Open Access Article

        2 - Determined by neutron radiation absorbed dose to the liver in practice
        seyd alireza Mousavi Shirazi
        In this article, a real liver tissue and soft tissue on the front of (such as fat and skin) decomposed to constituent elements And then irradiation with neutrons in radiotherapy action takes place. . This could be all about the treatment of liver cancer. The absorbed do More
        In this article, a real liver tissue and soft tissue on the front of (such as fat and skin) decomposed to constituent elements And then irradiation with neutrons in radiotherapy action takes place. . This could be all about the treatment of liver cancer. The absorbed dose in the liver as a result of collisions between neutron core elements that make up the liver tissue was determined then obtained interesting results in this regard. In this cross - sectional study of liver tissue, the means of neutron irradiation to put And the absorbed dose or energy absorbed in each of the ingredients of liver tissue is obtained. The results of descriptive statistics using excel v2010 and spss v16 software were analyzed. The findings suggest there if the compounds in the liver, and skin following their elements, such as hydrogen, oxygen, carbon, nitrogen, sulfur and sodium, Absorbed dose levels of the constituent elements of the liver, and skin followed, each with mass numbers different. The maximum value of absorbed dose and the frequency of the element hydrogen. Determined by neutron radiation absorbed dose to the liver in practice. Manuscript profile
      • Open Access Article

        3 - Comparison the effect of melatonin and the selective inhibitor of serotonin reuptake citalopram drug on the ultrastructure of liver tissue and hepatic enzymes in Adult Female three-spotted gourami Fish (Trichogaster trichopterus)
        Mohammadreza Pouravaz طاهره ناجی Homayon Hosseinzadeh sahafi
        Background & Aims: Most of the various drugs that are used to treat various diseases are metabolized in the liver. The purpose of this study is to investigate the effect of melatonin and selective serotonin reuptake inhibitor drug citalopram on liver tissue ultrastr More
        Background & Aims: Most of the various drugs that are used to treat various diseases are metabolized in the liver. The purpose of this study is to investigate the effect of melatonin and selective serotonin reuptake inhibitor drug citalopram on liver tissue ultrastructure and liver enzymes in adult female Trichogaster. Materials & Methods: For this purpose, 120 pieces of Trichogaster with an average weight of 4.23 ± 0.70 g divided into eight groups of 15, which included the control groups, solvent intact, three groups which received citalopram with a dose of 5, 10 and 20 mg/kg and three treatment groups receiving melatonin with doses of 10, 50, and 100 mg/kg. A dose of 0.02 ml of the drug was injected intramuscularly between the dorsal fin and the lateral line every other day for 10 times, over a period of 20 days. Then, the fish were euthanized and dissected. Results: The results showed that melatonin and citalopram had a significant effect on the level of all liver enzymes compared to the control groups (P<0.05). The highest levels of ALT, AST and ALP were measured after the injection of 20 mg/kg citalopram (P<0.05). In fish treated with the highest concentration of melatonin and all concentrations of citalopram, dissociation between hepatocytes and expansion of sinusoids occurred. Fat vacuoles were formed in high concentrations of melatonin and citalopram. Conclusion: Therefore, melatonin at a concentration of 100 mg/kg and citalopram at a concentration higher than 5 mg/kg have a negative effect on the ultrastructure of liver tissue and liver enzymes. Manuscript profile
      • Open Access Article

        4 - The Investigation of 2-Phenoxyethanol on Liver Tissue ofBarbus grypus
        نرگس جوادزاده محمدهاشم تیموری حدیده معبودی
        This study examined the histopathological effects of anesthetic 2-phenoxy ethanol on liver of Barbus grypus. In this study, a total of 30 Barbus grypus with sizes of 100 ± 2 g were selected. Water temperature with an average of 20°C. Fish were exposed to anesthetic 2-ph More
        This study examined the histopathological effects of anesthetic 2-phenoxy ethanol on liver of Barbus grypus. In this study, a total of 30 Barbus grypus with sizes of 100 ± 2 g were selected. Water temperature with an average of 20°C. Fish were exposed to anesthetic 2-phenoxy ethanol with ascending concentrations of 400, 600 and 700 mg/l for 90 second. Then first stage was"an hour" and the second was "three days after anesthesia" liver biopsy was taken samples were stained at 5-micron sections with hematoxylin – eosin method. Microscopic observations showed the effects of 2-phenoxyethanol on the liver at the dose of 700 mg/l create vacuolization, enlargement offat cells and dilatation of the hepatic sinusoids. At doses of 400 and 600 mg/l, this effect was less. Manuscript profile
      • Open Access Article

        5 - Effects ofMelissa officinalisExtractonLiver Enzymes and Histologyin Mice ر
        مهرداد مدرسی صفیه گلخنی مهران مجلسی
        Balm (Melissa officinalis) has many medical properties including relaxing, anti oxidant, and anti bacterial. This study was conducted to investigate the effect of hydro alcoholic extract of balm on activity of liver enzymes including AST, ALT, and ALP and also liver tis More
        Balm (Melissa officinalis) has many medical properties including relaxing, anti oxidant, and anti bacterial. This study was conducted to investigate the effect of hydro alcoholic extract of balm on activity of liver enzymes including AST, ALT, and ALP and also liver tissues variation in Balb/C mice. In this experimental study, samples were randomly divided into fivegroups (three treatment groups, placebo and control group) with eight members in each group. Groups were kept under similar conditions. Hydro alcholic extract was prepared in three doses (50,100, and 200 mg/kg) and were IP for twenty days. Normal saline was used for placebo group. After the last injection blood samples were taken and liver tissues were separated. Changes of AST, ALT, and ALP enzymes was evaluated using one way variance analysis and SPSS program (P ر Manuscript profile
      • Open Access Article

        6 - The Effect of Different Levels of Dietary Manganese on Antioxidant Activity, Liver Enzymes and Liver Histology in Reared Young Beluga (Huso huso)
        Fatemeh Hemmati Hossein Khara Habib Vahabzadeh Roudsari Rezvanollah Kazemi
        This research aims to determine the effect of different amounts of dietary manganese on antioxidant activity, liver enzymes and, liver tissue of rearing young beluga (Huso huso) from October to December 2022 at the Dr. Beheshti Reproduction and Genetic Stock Restoration More
        This research aims to determine the effect of different amounts of dietary manganese on antioxidant activity, liver enzymes and, liver tissue of rearing young beluga (Huso huso) from October to December 2022 at the Dr. Beheshti Reproduction and Genetic Stock Restoration Center of Sturgeon in Rasht, Guilan province. For this study, 180 pieces of beluga with an average initial weight of 266 ± 3.05 grams underwent a two-week adaptation period in the breeding environment, in six treatment groups and each treatment with three repetitions, with concentrations of 5 (Mn1), 10 (Mn2), 15 (Mn3), 20 (Mn4) and 25 (Mn5) mg of manganese sulfate monohydrate (MnSO4H2O) per kilogram of food and control treatment (Mn0) without adding manganese sulfate supplement were carried out in two months. At the end of each month, three pieces of fish were selected from each repetition, blood was collected and their livers were sampled for histological studies. The results revealed a significant difference in catalase and glutathione peroxidase levels among the experimental treatments (p<0.05) and their maximum amount was the control treatment fish, while superoxide dismutase levels did not differ significantly (p<0.05). Among the liver enzymes, Alkaline-phosphatase and aspartate-aminotransferase had a significant difference between the control treatment and other experimental treatments (p<0.05), but the alanine-aminotransferase enzyme had no significant difference (p<0.05). Also, different forms of tissue damage were observed in the liver tissue of all treatments, even the control (atrophy, biliary stagnation, Fat degeneration and, cellular necrosis). Based on the results of this research, the levels of 10-15 mg of dietary manganese could improve antioxidant activities, liver enzymes and reduce liver tissue damage in breeding young beluga. Manuscript profile
      • Open Access Article

        7 - Oxidative Stress Enzymes and Liver Tissue Changes of Male Rats under the Influence of Dust in Different Cities of Khuzestan Province
        Najmeh Soleimani Mohammad Reza Dayer Tayebeh Mohammadi Hassan Faridnouri
        The city of Ahvaz is considered the most polluted city in the world by blowing dust from neighboring countries which makes this study important. The results show that the smaller the particles, the more permeable they become and pass through the respiratory filters and More
        The city of Ahvaz is considered the most polluted city in the world by blowing dust from neighboring countries which makes this study important. The results show that the smaller the particles, the more permeable they become and pass through the respiratory filters and causing disease. In this study, the effect of fine particulate matters in different cities of Khuzestan province of Iran was compared on the liver histology and oxidative stress enzymes of male rats. 30 adult male rats were divided into six equal groups including control, Ahvaz, Ramhormoz, Andimeshk, Abadan, and Susangard which were treated for two months. The results of serum oxidative stress enzyme activity increased only for the glutathione peroxidase in Ramhormoz and Abadan groups. The histological examination of liver revealed bleeding, mild hyperemia, and changes in hepatocyte cells. The nuclear area in central vein region, hepatocyte area&nbsp;in portal, and vein regions showed significant changes. Moreover, kupffer cell number of the portal region significantly increased in Ahvaz, Abadan, and Andimeshk groups. Therefore, due to different heavy metals composition, fine dusts have different effects on blood and liver parameters which depend on their amount and duration of exposure. &nbsp; Manuscript profile