List of Articles Oxytocin

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  1 - Synergistic Effect of Oxytocin with mu Opioid Receptor Agonist on Central Control of Food Intake in neonatal Chickens
  Faramarz Raji-Dahmardeh morteza zendehdel bita vazir Ahmad Asghari Negar Panahi
  Introduction & Objective: The opioidergic system and its different receptors play an important role in the central control of food intake in birds. On the other hand, the decreasing effect of oxytocin on food intake of birds has been observed. The present study was More

  Introduction & Objective: The opioidergic system and its different receptors play an important role in the central control of food intake in birds. On the other hand, the decreasing effect of oxytocin on food intake of birds has been observed. The present study was conducted to investigate the synergistic effects of oxytocin with opioid receptors on food intake in neonatal layer chickens.Materials and Methods: In this study, three experiments were designed, so that each experiment included one control group and three treatment groups. In all groups, birds received intracerebroventricular injection of diluent solution or drug solution after 3 hours of food deprivation. In the first experiment, normal saline, oxytocin(0.16 nmol), DAMGO(62.5 picomol) (agonist of mu-opioid receptors) and oxytocin plus DAMGO were injected. The other experiments were conducted as experiment 1, but instead of DAMGO, DPDPE (20 nmol)(agonist of delta opioid receptors) in the experiment 2 and U-50488H (10 nmol)(agonist of kappa opioid receptors) in experiment 3 were injected either alone or in combination with oxytocin. After the injection, water and food were freely available to the birds and then cumulative food intake (gr) was measured based on the ‎percentage of the body weight.Results: The results of the present study showed that sub effective dose injection of oxytocin plus DAMGO significantly reduced food intake in layer chickens (P<0.05).Conclusion: According to the results of the present study, there is probably a synergistic effect between oxytocin with mu-opioid receptors agonist on food intake control of neonatal layer chicks. Manuscript profile
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  2 - Synergistic Effects of Noradrenalin, Serotonin, and Oxytocin with Nesfatin on Central Control of Food Intake in Broiler Chickens
  Takrokh Ashtari tavandashti , Morteza , Zendehdel Mehdi Rahnema Shahin Hasanpour , Masoumeh Asle-Rousta
  Introduction & Objective: Appetite modulation is a set of physiological mechanisms that influence the various areas of the central nervous system. Noradrenaline, serotonin, and oxytocin have an important role in the central control of food intake in birds. On the ot More

  Introduction & Objective: Appetite modulation is a set of physiological mechanisms that influence the various areas of the central nervous system. Noradrenaline, serotonin, and oxytocin have an important role in the central control of food intake in birds. On the other hand, nesfatin decreases food intake in birds. Therefore, the aim of this study was to explain the synergistic effects of noradrenalin, serotonin, and oxytocin with nesfatin on food intake in neonatal broiler chickens.Materials and Methods: A total of one hundred and forty-four neonatal chicks were randomly divided into three experimental groups. Each experiment had a control group and three treatment groups (n=12 in each group). In all experiments, 3-hour food-deprived birds received intracerebroventricular ‎injections of either control diluent or drug solution. Then, the birds had ad libitum access to the ‎food and fresh water, and then cumulative food intake (gr) was measured based on the ‎percentage of the body. In the first experiment, normal saline, noradrenalin, nesfatin, and noradrenalin plus nesfatin were injected.‎ In the second experiment, normal saline, serotonin, nesfatin, and serotonin + nesfatin were injected. In the third experiment, normal saline, oxytocin, nesfatin, and oxytocin plus nesfatin were injected.Results: The results of the present study showed that co-injection of noradrenalin and nesfatin, serotonin plus nesfatin, and oxytocin plus nesfatin significantly reduced food intake in broiler chickens (P<0.05).Conclusion: According to the results of the present study, there is probably a synergistic effect between noradrenalin, serotonin, and oxytocin with nesfatin on food intake control of neonatal broiler chickens.  Manuscript profile
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  3 - تأثیر روش شیردوشی با اکسی ‌توسین بر عملکرد شیردهی و طول دوره شیردهی گوسفند
  M. Nezamidoust S. Razzaghzadeh E. Ezati R. Ghorbani
  برآورد میزان بازده شیر با استفاده از یک روش دقیق جهت سنجش نیازهای تغذیه‌ای، ارزیابی پتانسیل ژنتیکی، رشد و زنده مانی بره، تصمیم‌گیری‌های مدیریتی و بهبود صفات عملکردی گله گوسفند ضروری است. تزریق اکسی توسین جهت تخمین میزان ترشح شیر در گوسفند استفاده می‌شود. اکسی توسن یک هو More

  برآورد میزان بازده شیر با استفاده از یک روش دقیق جهت سنجش نیازهای تغذیه‌ای، ارزیابی پتانسیل ژنتیکی، رشد و زنده مانی بره، تصمیم‌گیری‌های مدیریتی و بهبود صفات عملکردی گله گوسفند ضروری است. تزریق اکسی توسین جهت تخمین میزان ترشح شیر در گوسفند استفاده می‌شود. اکسی توسن یک هورمون عصبی که در سیستم هیپوتالاموس-هیپوفیز پسین تولید شده و در پاسخ به تحریک نوک پستان به داخل خون آزاد می‌شود. اکسی توسین دارای اثر گالاکتوپوئتیک و با تأثیر بر فرایند خروج شیر از طریق فعالیت ترشحی و انقباض سلول‌های مایواپتلیال نقش مهمی در شیردهی بازی می‌کند. جهت بررسی اثر تزریق اکسی‌ توسین بر بازده شیرده، ترکیبات شیر و طول دوره شیردهی میش‌ها در کل طول دوره شیردهی، یکصد رأس گوسفند نژاد ماکوئی با زایش و پرورش یک بره به دو تیمار، گروه 1 (شیردوشی و تخلیه کامل پستان با دست بعد از تزریق عضلانی 5/2 واحد بین المللی اکسی توسین) گروه 2 (شیردوشی و تخلیه کامل پستان با دست) اختصاص یافتند. داده‌ها از روز چهاردم بعد از زایش با فاصله دو هفته‌ای در میان رکورد برداری شدند. گرو دریافت کننده اکسی توسین به طور معنی‌داری میانگین شیر تولیدی روزانه (3/562 درمقابل 4/301 گرم) و مقدار کل شیر (6/93 درمقابل 5/38 کیلوگرم) بیشتری در مقایسه با گروه شاهد تولید کردند (05/0>P). طول دوره شیردهی به ترتیب 7/145 روز برای گروه اکسی توسین و 2/115 روز برای گروه شاهد بود (038/0=P). تزریق اکسی توسین بازده پیک شیر و تداوم شیردهی میش‌ها را افزایش داد (05/0>P). در حالیکه زمان پیک کوتاه‌تر (1/34 درمقابل 2/39) برای گروه اکسی توسین مشاهده شد (043/0=P). استفاده از اکسی توسین درصد چربی شیر (73/6 درمقابل 86/5) را در مقایسه با میش‌های گروه شاهد افزایش داد (029/0=P). اما با تزریق اکسی توسین هیچ تفاوتی در درصد پروتئین و لاکتوز شیر مشاهده نشد (05/0>P). روند صعودی ممانعت ازخروج شیر سرتاسر دوره شیردهی به دنبال دوره منحصراً شیرخواری و سپس شیر‌دوشی با دست، نیاز به اکسی توسین را جهت نگهداری سلول‌های پستان و تداوم شیردهی در میش‌ها مستلزم می‌نماید و تأیید می‌کند که اکسی توسین با غلبه بر مکانیسم‌های پس خور منفی حاصل از شیر در اطراف آلوئل و با افزایش انتقال وزیکول‌های ترشحی داخل سلولی و انقباض سلول‌های مایواپتلیال، مقدار تولید شیر و طول دوره شیردهی میش‌ها را افزایش می‌دهد که یک تکنیک مفید جهت تضمین خروج شیر آلوئلی و تخلیه نرمال شیر از محفظه سیسترن می‌باشد. Manuscript profile
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  4 - Effect of Exogenous Oxytocin Administration on the Performance of Lactating Nili Ravi Buffalo
  A. Faraz N.A. Tauqir A. Waheed A. Hameed
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  5 - Evaluation of Salivary Oxytocin Level in Pregnant Women during Pregnancy in Fatemiyeh Hospital of Hamadan, Iran
  Zahra Karami Hamid Reza Abdolsamadi Lida Samie Shohre Alimohammadi Alireza Soltanian
  10.22034/jchr.2021.1920489.1244
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  6 - Clinical report of an Idiopathic Hypogonadotrophic Hypogonadism in a seven year old dog
  اورنگ Ataee Amarluii, , S Naghibzadeh
  On a 7-years-old dog with Azoospermia three conventional drugs in breeding techniques were tested to assess the effects and reproductive improvement of them. the Drugs that chosen include gonadotropin (GnRH) in commercial name Cystorelin، 50 micrograms subcutaneously More

  On a 7-years-old dog with Azoospermia three conventional drugs in breeding techniques were tested to assess the effects and reproductive improvement of them. the Drugs that chosen include gonadotropin (GnRH) in commercial name Cystorelin، 50 micrograms subcutaneously 60 minutes prior to sperm collection , prostaglandin (PGF2α) in commercial name Veteglan , 0/005 mg/kg subcutaneously 15 minutes prior to sperm collection and Oxytocin 10IU per dog intramuscularly 10 minutes prior to sperm collection. Semen collected from this animal by manual semen collection technique and we had 7 days sexual rest between each collection. during the semen collection the dog’s libido was assessed and then semen Volume , Semen PH , semen color , semen concentration per ml ,total count of spermatozoa , progressive motility forward percent , morphologically normal spermatozoa percent and Total normal motile spermatozoa (TMNS) was evaluated. The samples did not show any traces of semen quality change when dog received prostaglandin and oxytocin and there is no spermatozoa in that samples. But when the sampled animal was under the influence of gonadotropin therapy semen quality improved dramatically in addition we have one billion and twenty-four millions of spermatozoa as the total count of the sample. Two hypotheses are proposed for this quality improvement. The frst one say the prescribing of gonadotropin in this dog, increased the animal blood testosterone index and stimulate the seminiferous ducts to released spermatozoa. The second one say because of the clinical condition of the animal it seems to had IHH syndrome and during the administration of gonadotropin the body hormonal system was regulated and released the sperm cells. Finally, it can be concluding that the use of gonadotropins may be improving the quality of semen of animals that have Azoospermia with source of hormonal abnormality.   Manuscript profile