List of Articles One-pot reaction

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  1 - Evaluation of higher-order multicomponent reactions and biological applications of their products
  sima kalhor sima kalhor زهرا کلهر
  Multicomponent reactions (MCRs) are by far the most successful class of reactions leading to high structural diversity and molecular complexity through a single transformation. As part of the ongoing search for pharmacologically active lead structures, the obtained stru More

  Multicomponent reactions (MCRs) are by far the most successful class of reactions leading to high structural diversity and molecular complexity through a single transformation. As part of the ongoing search for pharmacologically active lead structures, the obtained structural diversity allows for the fast exploration of a large chemical space. Not surprisingly, the development of MCRs, leading to new structural frameworks or serving as key transformations in the total synthesis of natural products, has expanded rapidly over the last few decades. To date a multitude of new three- and four-component reactions have already been described; however, examples of ‘‘higher-order’’ MCRs where five or even more components are combined in a single reaction vessel are remarkably scarce. With the growing interest for biologically active small molecules at the end of the 20th century, the application of MCRs to create libraries of such small, drug-like molecules was investigated with a steadily increasing intensity by industry and academia as a result of its superiority over other approaches (i.e. the use of readily available starting materials, inexpensive and easy to carry out chemistry, broad product spectra, high diversity in few steps, ease of automation, etc). This tutorial review aims to critically describe the developments achieved in recent years, charting the ideas, challenges, and milestone reactions that were essential for the progress of this field. Manuscript profile
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  2 - Three-component Process for the Synthesis of Some Thiophene Derivatives Using Water as a Green Media
  Ali Varasteh Moradi
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  3 - Application of ZnO Nanorods for the Synthesis of Thiazole Derivatives via Multicomponent Reactions in Water
  Ali Varasteh Moradi
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  4 - Solvent-Free Multicomponent Reactions of Dithiocarbamates, Activated Acetylenes and Isocyanides
  F. Rostami-Charati Z. Hossaini R. Hajinasiri
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  5 - Application of 2-methylpyridinum p-toluenesulfonate ([2-MPy][p-TSA]) as an efficient catalyst for the one-pot synthesis of hexahydroquinolines-3-carboxamides
  Matin Asadi Masoud Mokhtary
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  6 - Water as the Green Media for the Synthesis of Isoquinoline Derivatives
  Rokhsar Pahlavan Maedeh Najaf Zinatossadat Hossaini
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  7 - SOLVENT-FREE SYNTHESIS OF PYRROL DERIVATIVES USING MULTICOMPONENT REACTIONS OF 1,3-‎DICARBONYLS, ACTIVATED CARBONYL COMPOUNDS, AND PRIMARY ALKYLAMINES
  Faramarz Rostami-Charati Mehdi Shahraki Mohammad R Hosseini- Tabatabaei Zinatossadat Hossaini
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  8 - SOLVENT-FREE SYNTHESIS OF PYRROL DERIVATIVES USING MULTICOMPONENT REACTIONS OF 1,3-‎DICARBONYLS, ACTIVATED CARBONYL COMPOUNDS, AND PRIMARY ALKYLAMINES
  Faramarz Rostami-Charati Mehdi Shahraki Mohammad R. Hosseini- Tabatabaei Zinatossadat Hossaini
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  9 - A Simple and one-pot synthesis of imintriazole derivatives under Solvent-free conditions
  Narges Ghasemi Parvaneh Firoozi Khanghah Mahboubeh Ghasemian Dazmiri
  10.30495/iranjoc.2023.699826
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  10 - Preparation and characterization of ionic liquid functionalized SBA-15 and its application in the synthesis of 2,3-dihydroquinazolinones
  Ghodsi Mohammadi Ziarani Leila Seiedakbari Parisa Gholamzadeh Alireza Badiei
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  11 - 1-(1-Propylsulfonic)-3-methylimidazolium chloride Brønsted acidic ionic liquid catalyzed one-pot synthesis of 14-aryl-14H-dibenzo[a,j]xanthene derivatives under solvent-free conditions
  Sima Abbaspour Mogharab Torabi Jafroudi Shima Haghi Sohan Rezayati
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  12 - Nano TiO2@SiO2 as an efficient and reusable catalyst for the synthesis of multi-substituted imidazoles
  Maryam Haghighi Kobra Nikoofar
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  13 - Boric acid as a highly efficient and reusable catalyst for the one-pot synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions
  Sobhan Rezayati Rahimeh Hajinasiri Zahra Erfani Saman Rezayati Saeid Afshari-sharifabad
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  14 - A Novel Efficient Solid Acid Nanocatalyst for the Synthesis of 1'-Aryl-2'-(2-oxoindolin-3-yl)spiro[indoline-3,5'-pyrroline]-2,3'-dione Derivatives
  کبری نیکوفر زهرا خادمی شیوا خانی
  Para-toluene sulfonic acid embedded on nano silica )ρ-TSA@nano SiO2( has been synthesized via a simple procedure and characterized by fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), and scanning electron microscopy (SEM) More

  Para-toluene sulfonic acid embedded on nano silica )ρ-TSA@nano SiO2( has been synthesized via a simple procedure and characterized by fourier transform infrared spectroscopy (FT-IR), energy-dispersive X-ray spectroscopy (EDX), and scanning electron microscopy (SEM) techniques. The synthesized nanocatalyst has been utilized to accelerate the one-pot multicomponent condensation reaction of isatins, anilines, and acetone to obtain the corresponding 1'-aryl-2'-(2-oxoindolin-3-yl)spiro[indoline-3,5'-pyrroline]-2,3'-diones at water media under reflux conditions. Utilization of H2O as available and green solvent, excellent yields of products, short reaction times, avoidance of by-products which could be obtained via Aldol condensation of acetone, easily-handle, inexpensive, non-toxic, and heterogeneous nano acid catalyst are some advantageous of the reported method. The recovery and reusability of the nano catalyst has been examined for four runs without activity loss Manuscript profile