• List of Articles Leukocytes

      • Open Access Article

        1 - Compare the effects of two intense interval training (HIIT) protocol on some Immunological indices in young overweight girls
        azizeh ahmadi rasoul dokhtabdiyan
        this study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23 More
        this study purpose is to determining the effect of two types high intensity exercise (HIIT) on some Immunological indices in young overweight girls. 24 girls with age 25/75±1/18 y, height: 161/29± 4/23cm, weight 74/51±6/27 kg، fat 30/70± 2/23%, BMI 28/66±1/89 kg/m2 voluntarily participated and randomly divided into three experimental HIIT1 group (n=8), HIIT2 group (n=8) and control group (n=8). Group HIIT1 in each session running four sets 30s with 19 to 20 rate of perceived exertion (RPE) Borg scale and two minutes of rest between sets. HIIT2 group running four sets of 60 s with the same intensity and four minutes rest between sets, training protocol performed three times a week and performed four weeks. 48 hours before and 48 hours after exercise, blood samples were taken. For analyzing data, use Mixed between-within Subjects analysis of variance in level of (P<0.05). mean percent of LYM, NEUT and NEUT levels did not change significantly (P>0.05). The mean of lymphocytes showed significant increase only in Group HIIT2 (P=0.005), difference between groups was not significant (P>0.05). leukocytes in the Both experimental groups was significant increase (P<0.05). The mean of immunoglobulin A in both experimental groups showed a significant increase (p<0.05). In the mean of immunoglobulin G, significant changes were observed only in HIIT1 group (p<0.05). immunoglobulin M did not change significantly in any of the groups (p>0.05). it seems that Short-term HIIT increase leukocyte counts and immunoglobulin A and G to a greater extent than medium-term HIIT. Manuscript profile
      • Open Access Article

        2 - Differential leukocyte counts in German shepherd dogs following Alloxan-induced diabetes mellitus
        M.R Valilou علیرضا Lotfi
        Diabetes mellitus involves most physiological functions include hematopoiesis and immune system.  In this research, ten male German shepherd dogs with same age were provided; five dogs were considered as control and  five of them were considered as experimenta More
        Diabetes mellitus involves most physiological functions include hematopoiesis and immune system.  In this research, ten male German shepherd dogs with same age were provided; five dogs were considered as control and  five of them were considered as experimental groups; pre- and post- diabetes induction. The examinations were conducted to guarantee their health and absence of diabetes with Intra-venous glucose tolerance test (IVGTT) has been approved, according to Islamic Azad university animal ethics recommendations. Alloxan monohydrate with 100 mg/kg in was injected intravenously for experimental group. The blood samples were collected before and after diabetes induction (after 45 days). Next, leukocytes number includes neutrophil, lymphocyte, monocyte, eosinophil and basophil percents were measured. According to obtained results, eosinophil and basophil rates hadn’t significant changes after diabetes induction. But neutrophil, lymphocyte and monocyte percents had significant changes after diabetes induction; while neutrophils were 82.3% in diabetic dogs (in comparison with 72.38% for control and 69.53% for pre-diabetes). Lymphocyte and monocyte counts were lower in diabetic dogs when they are compared with pre-diabetic and control measures (lymphocyte: 22.79, 26.24 and 14.59% and monocyte 2.05, 2.58 and 1.81% respectively for control, pre- and post-diabetes groups. It is seem that diabetes-related lymphocytes dysfunction may caused considerable lymphocytes rise in diabetic dogs in comparison with control or pre-diabetes groups. It was concluded that diabetes induction in German shepherd dogs may caused lymphocyte and monocyte numbers and neutrophils rises. It is suggested that impaired glucose and glutamine metabolism in diabetic condition and high demands of neutrophils for these substances may cause neutrophils rises in diabetic dogs. It seems that further studies about possible reasons of leukocytes number changes in diabetic dogs are necessary.   Manuscript profile