• List of Articles IL_1&beta

      • Open Access Article

        1 - The effect of six weeks aerobic training and cinnamon extract on IL_1β gene expression in fat tissue of obese male feeded by high fat diet.
        amin rigi Tahereh Bagherpoor nematallah nemati
        Background and Aims: In obese people, the expression level of interleukin 1 beta is higher, so that the expression level of interleukin 1 beta has a direct positive relationship with the level of body mass index and fat mass. The present study aimed to determine the eff More
        Background and Aims: In obese people, the expression level of interleukin 1 beta is higher, so that the expression level of interleukin 1 beta has a direct positive relationship with the level of body mass index and fat mass. The present study aimed to determine the effects of six weeks of aerobic exercise, consumption of cinnamon extract and high-fat food on the expression of interleukin-1 beta gene in the adipose tissue of male rats fed with a high-fat diet using two-month-old male Wistar rats.Materials and methods: 50 two-month-old male rats were divided into five control groups, high-fat diet, cinnamon extract and high-fat diet, aerobic exercise and high-fat diet, and aerobic exercise and cinnamon extract and high-fat diet after two weeks of keeping under controlled conditions. were divided Cinnamon extract at the rate of 200 mg per kilogram of body weight and emulsion of high-fat food in excess of water and normal rodent food daily at the rate of 1.5 mg per kilogram of body weight were given by gavage for six weeks. became. The exercise group participated in an aerobic exercise program on a treadmill five days a week for six weeks. The mean of the research variables among the groups (except the control group) were compared with one-way analysis of variance and Bonferroni tests in order to determine the differences between the groups. The mean of the research variables among each group was compared with the control group with the purpose of determining intra-group differences, with the one-sample t-test at a significance level of p ≥ 0.05.Results: The difference in body weight and fat tissue weight was significant among all groups. The difference between the variable averages of interleukin-1 beta in adipose tissue of male rats fed with high-fat diet after six weeks of aerobic exercise, consumption of cinnamon extract and high-fat food was significant.Conclusion: It seems that the effects of high-fat diet, combination of high-fat diet and aerobic exercise, combination of high-fat diet and cinnamon and combination of high-fat diet and aerobic exercise and cinnamon on interleukin-1 beta variable in adipose tissue are significant and significant. to have Manuscript profile