• Home
  • Humulus lupulus
    • List of Articles Humulus lupulus

      • Open Access Article

        1 - Study on sedative effects of different fractions of Hop (Humulus lupulus L.) extract compared with diazepam in rats
        رامین Shishehgar علی Rezaie ایلیاد Iesa beiglou محمد Jalilzadeh Hedayati CH Ahmadizadeh سلما Asl Faeghi A.R Ebadi
        Humulus lupulus is a medicinal plant which in Farsi is called "razak". The purpose of this research is, studying the sedative effects of polar, semi polar and non polar fractions extracted from Hop (Humulus lupulus. L) in comparison with diazepam in the animal model of More
        Humulus lupulus is a medicinal plant which in Farsi is called "razak". The purpose of this research is, studying the sedative effects of polar, semi polar and non polar fractions extracted from Hop (Humulus lupulus. L) in comparison with diazepam in the animal model of Rat. For conducting this research polar, semi polar and non polar fractions extracted from Hop based on the polarity of solvent. Then study continued with the injection of obtained extracts and other medicines to different groups of Wistar breed of rats. First group was injected with 100mg/kg of Polar fraction extract the second group, with 100mg/kg of Semipolar extract, the third group, with 100 mg/kg of non-polar extract of Humulus lupulus the fourth group with 2 mg/kg of Diazepam the fifth group with the same volume of DMSO used as solvent of injectable medicines an the sixth group was the control group and did not receive any drug. The method of injection was Intra peritoneal (IP) form. Statistical diagrams and results showed a significant decreasing of anesthetic induction time and increasing of sleeping time of Ketamin induced anesthesia, after IP injection of the Polar fraction extract of Humulus lupulus. The results obtained showed that the polar-fraction extract of Humulus lupulus has more sufficient sedative effects than diazepam and other under studied groups. Manuscript profile
      • Open Access Article

        2 - Using of OSC-PLS chemometry method for simultaneous determination of Gallium and Nickel in Echinacea purpurea and Humulus lupulus soil by UV-Vis Spectrophotometer
        مازیار Ahmadi Golsefidi R.A Rajabzadeh H.R Jalilian
         Echinacea purpurea and Humulus lupulus are two strategic medicinal plants in Golestan province and have many usage in pharmaceutical and food industries. Heavy metals like gallium and nickel in a standard concentration range are accepted for the soil of these two More
         Echinacea purpurea and Humulus lupulus are two strategic medicinal plants in Golestan province and have many usage in pharmaceutical and food industries. Heavy metals like gallium and nickel in a standard concentration range are accepted for the soil of these two plants. Extra concentration of the elements can aggregate and poisoned the metabolite activities in plants. Thus an accurate determination of concentration method is needed to control the amount of heavy metals in such a soils. Orthogonal signal correction – Partial least squares modeling is a powerful multivariate statistical tool applied to spectrophotometric simultaneous determination of mixtures of Gallium and Nickel. The method is based on the formation of the complex of PAN with Gallium and Nickel. The ISBO membrane shows enhanced selectivity for Ga3+ and Ni2+ but absorption spectra of these two complexes overlap strongly, thus it is difficult to analyze the compounds in their mixtures. In this study, the calibration model is based on absorption spectra in the 400-650 nm range for 25 different mixtures of Gallium and Nickel. A series of synthetic solutions containing different concentrations of Gallium and Nickel was used to check the prediction ability of the OSC-PLS model. The RMSEP were 0.3587 and 0.8496 for Gallium and Nickel, Respectively. Amount of Ga3+ and Ni2+ were determined 0.08 and 3.1 ppm in the plant soils respectively. Manuscript profile