List of Articles Fumaria parviflura

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  1 - Interaction Between Fumaria parviflura Aqueous Extract and Cholorambocil on Spermatogenesis in Rats
  مونا سوری میترا حیدری نصرآبادی عبدالحسین شیروی زه حبیبی
  Introduction:Fumaria parviflura belongs to the Fumariacea family. Medicinal properties of Fumaria derived from green fork-like leaves and violet flowers that the antioxidant effects of these items has been recently noticed. Cholorambocil (CHL) is an effective substance More

  Introduction:Fumaria parviflura belongs to the Fumariacea family. Medicinal properties of Fumaria derived from green fork-like leaves and violet flowers that the antioxidant effects of these items has been recently noticed. Cholorambocil (CHL) is an effective substance of the leukeran that is used against the human neoplasm disease. It is demonstrated that CHL in specific dosage has severe destructive effects on the testis tissue.The aim of this study is to investigate the effect site of CHL in testis tissue and protective role of the Fumaria aqueous extract, against .Materials and Methods:Wistar male rats divided into 3 groups: control, control2 , experimental 1,2,3,4 (n=7). The control group received distilled water, the c0ntrol2 group received distilled 10 mg/kg w.b. CHL , the experimental groups1, received distilled 150 mg/kg w.b Fumaria aqueos extract and the experimental groups 2,3,4 received 150,250,350 mg/kg w.b CHL and 150, 250 ,350 mg/kg w.bFumaria aqueous extract and 10mg/kg.wb CHL through oral gavage respectively. After 15 days rats were anesthesized and blood test performed. Rats sacrificed and the Testis were removed. the volume and weight of the testis were measured and the tissues were fixed. The preparation of Tissue sectioning accomplished by Handamp;E staining.Sertoli and spermatogenic cells counted with light microscopeResults and Discussion:Statistical analyzes showed that CHL has significantly reduced cell groups specially primary spermatocyte and Fumaria aqueous extract has significantly restrained this effect Manuscript profile
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  2 - The Evaluation of the Interference effect of Fumaria parviflora Ethanolic Extract and Medicine Chlorambucil on the Spermatogenesis of Male Wistar Rat
  زهرا حبیبی میترا حیدری نصر آبادی عبدالحسین شیروی مونا سوری
  This study the effects of ethanolic extract of Fumaria with the scientific name of Fumaria parviflora that belongs to the family of Fumariacea as an anti-oxidan and interference of it with chlorambucil in testis tissue is considered. The aim of this study is to investig More

  This study the effects of ethanolic extract of Fumaria with the scientific name of Fumaria parviflora that belongs to the family of Fumariacea as an anti-oxidan and interference of it with chlorambucil in testis tissue is considered. The aim of this study is to investigate the effect site of chlorambucil in testis tissue and protective role of the Fumaria ethanolic extract, against male wistar rats is grouped in six, seven group(n=7). The witness 1 group was served with only liquid oil; the witness 2 group was served only with 10 mg/kg w.b. chlorambucil. The treatment 1 group 150mg/kg w.b Fumaria ethanolic extract, the treatment groups 2, 3, 4 were served with10 mg/kg w.b. chlorambucil and 150, 250, 350mg/kgw.b. Fumaria ethanolic extract respectively Chl via gavage. After 15 days the rats should be analysed and their testis were brought out and after the morphometry studies, they were studied histologically. Germinal epithelium is considered and the number of cells were counteddistinguish that chlorambucil in witness 2 group was very effective and the size of testis and the number of sperms were greatly decreased, but in treatment groups the changes were related to dosage of Fumaria ethanolic extract. Manuscript profile