List of Articles Creatine kinase

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  1 - The Effect of Selenium Supplementation on Serum Levels of Creatine Kinase, Lactate Dehydrogenase and Muscle Strength at Resting and after a Soccer Match in Young Soccer Players
  M. Azimi F. Moradi
  Introduction: Few researches have been carried out on the effect of selenium supplementation on muscle damage in athletes. The aim of this study is to investigate the effect of selenium supplementation on serum levels of creatine kinase (CK), lactate dehydrogenase (LDH) More

  Introduction: Few researches have been carried out on the effect of selenium supplementation on muscle damage in athletes. The aim of this study is to investigate the effect of selenium supplementation on serum levels of creatine kinase (CK), lactate dehydrogenase (LDH) and muscle strength at resting and after a soccer match in young soccer players. Materials and Methods: The research method was quasi-experimental and 19 young soccer players were selected among soccer players in Saghez city and were randomly divided into two experimental (supplementation, n=10) and control (placebo, n=9) groups. The assessments were carried out in three stages (pre-supplementation, post-supplementation, and immediately after the match). General characteristics of subjects, muscle strength, and circulating levels of LDH and CK were measured. The supplementation period was one month (one 200 µg/ml selenium capsule daily). The placebo group also consumed a starch capsule each day. In order to analyze the data, two factor analysis of variance with repeated measures were used at the significant level of P<0.05. Results: Selenium supplementation has no effect on muscle strength (bench-press p=0.790, leg-press p=0.912) and levels of CK (p=0.051) and LDH (p=0.244) at rest and after the soccer match. Conclusion: Selenium supplementation for one month and a daily intake of 200 μg does not appear to have a beneficial or harmful effect on muscle strength and circulating levels of enzymes indicating muscle damage at rest and following a soccer match in young soccer players. More research is needed to reveal various aspects of the issue. Manuscript profile
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  2 - The Effect of Ethanol Extraction of Aloe vera on Certain Biomarkers of Cardiovascular Disease in Mice Treated with Nanoparticles of Titanium Dioxide
  Fereshteh Javan Masoomi Jila Talat Mehrabad Roghayeh Babri Bonab
  Inroduction & Objective: The effect of ethanol extraction of Aloe vera on certain biomarkers of cardiovascular disease in mice treated with titanium dioxide nanoparticles was studied.Material and Methods: Mice were received titanium dioxide nanoparticles with density of More

  Inroduction & Objective: The effect of ethanol extraction of Aloe vera on certain biomarkers of cardiovascular disease in mice treated with titanium dioxide nanoparticles was studied.Material and Methods: Mice were received titanium dioxide nanoparticles with density of 100 milligrams per kg and ethanol extraction of aloe vera plant with density of 100, 200 and 300 milligrams per kg for 30 days. Plasma levels ofmalondialdehyde, rich sialic acid, troponin I and creatine kinase MB at the end of treatment was evaluated. The antioxidant activity of ethanol extraction in Aloe Vera using free radical DPPH and total phenol levels were considered.Results: The results showed that giving titanium dioxide nanoparticles through the stimulation of oxidative activity had a significant increase in plasma levels of malondialdehyde (MDA). Plasma levels of troponin I, creatine kinase MB and rich sialic acid also significantly increased. With increasing density of aloe vera, the total phenol and antioxidant activity of ethanol extraction increased. Giving the extraction significantly reduced the plasma levels of biomarkers of cardiovascular damage in mice treated with titanium dioxide nanoparticles.Conclusion:According to the results, ethanol extraction of aloe vera as an antioxidant compound is able to reduce the levels of cardiovascular damage in mice treated with titanium dioxide nanoparticles. Manuscript profile
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  3 - The effect of a session of intense resistance activity with glutamine supplementation on the relative expression of myogenin and myosin creatine kinase genes in the fast-twitch muscle fibers of adult male Wistar rats.
  mansoor mottahedi Tahereh Bagherpoor َArdeshir Zafari nematallah nemati
  Background & Aim: Despite the importance of resistance protocol and glutamine on hypertrophy, their effect on myogenic genes expression process is still unknown. Therefore, the aim of the present study was to investigate the effect of an intense resistance session w More

  Background & Aim: Despite the importance of resistance protocol and glutamine on hypertrophy, their effect on myogenic genes expression process is still unknown. Therefore, the aim of the present study was to investigate the effect of an intense resistance session with glutamine on Myogenin and Myosin creatine kinase gene expression in male Wistar rats. Materials & Methods: 30 8-week-old male rats with an approximate weight of 220±20 were prepared and divided into three groups, control, intense resistance training, and intense resistance training with glutamine, in a simple random manner. The training groups participated in a resistance session of climbing the ramp with 4 sets, 5 repetitions, 30 seconds of rest between repetitions and 2 minutes of rest between sets. Glutamine was once a day powder dissolved in 100 cc of distilled water at a dose of 5.5 grams per kilogram of body weight every day for 5 days. The Extensor Digitorum long muscle tissue was sent to the relevant laboratory to study the expression of Myogenin and Myosin creatine kinase genes. The relative fold change method was used to check gene expression data at a significance level of 5%. Results: The gene expression results showed that myogenin and myosin creatine kinase gene expression levels increased significantly as a result of a high-intensity resistance training session with glutamine compared to the control group, and this value was more pronounced in the resistance training group (p<0.05). Conclusion: It seems that an intense resistance training session is more effective than glutamine on the increase of myogenic genes. Manuscript profile
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  4 - The effects of glutamine on serum LDH and CK in rats following a session of resistance activity
  Shima Ebadi Ardeshir Zafari
  Muscle pain after resistance activities, which occurs due to the destruction of sarcolema, increases the serum levels of LDH and CK enzymes as indicators of muscle damage. The results have shown that the use of food supplements such as glutamine can be useful in reducin More

  Muscle pain after resistance activities, which occurs due to the destruction of sarcolema, increases the serum levels of LDH and CK enzymes as indicators of muscle damage. The results have shown that the use of food supplements such as glutamine can be useful in reducing the serum indicators of muscle damage. The aim of the present study is to determine the effect of glutamine supplementation on serum indicators of muscle damage, including the serum levels of LDH and CK enzymes following a session of resistance activity. The present experimental study was carried out using an animal model in the form of a 3 group’s research design with a control group. To this end, 30 six-week-old adult male Wistar rats were kept under controlled conditions for 2 weeks and were then divided into three equal groups, including control, and resistance activity with/ without glutamine supplementation. The glutamine supplementation group received the prepared emulsion by gavage of 200 mg/kg of body weight. After five days, both experimental groups participated in a session of resistance activity (namely, climbing a smooth ramp with one and a half meters height and a 85° decline) with 4 sets, 5 repetitions, 30 seconds of rest between repetitions and 2 minutes of rest between sets. The initial load was considered equal to 50% of the rats' body weight. One-way analysis of variance and Bonferroni's post hoc test were used at a significance level of p ≥ 0.05. The levels of CK and LDH enzymes were different in groups. A five-day glutamine supplementation before performing a session of resistance activity can cause a lower increase in the serum levels of CK and LDH enzymes as serum indicators of muscle damage, which indicates the protective effect of glutamine in maintaining the integrity and structure of cell membrane. Manuscript profile
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  5 - Effect of vitamin E supplementation on delayed onset muscle soreness in young men
  Mostafa Kashef
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  6 - Comparison of Six Weeks of Weight Training with a Combination of Beta Hydroxy-Beta Methyl Butyrate and Creatine Supplement and Two Weeks of Non-Training on Creatine Kinase and Lactate Dehydrogenase in Male Powerlifting Athletes
  Mojtaba Darvishkhadem Tahereh Bagherpour Nematollah Nemati
  10.22034/ascij.2022.1926127.1241
  The aim of this study was to compare six weeks of weight training with HMB and creatine supplementation and two weeks of non-training on creatine kinase and lactate dehydrogenase in male powerlifting athletes. Thirty-two male athletes aged 21 to 30 years were randomly d More

  The aim of this study was to compare six weeks of weight training with HMB and creatine supplementation and two weeks of non-training on creatine kinase and lactate dehydrogenase in male powerlifting athletes. Thirty-two male athletes aged 21 to 30 years were randomly divided into four groups of 8 people creatine, HMB, HMB + Cr, and weight training. The training program was designed for 6 weeks and four sessions per week. HMB group 3 grams of supplement on training days and 1 gram on non-training days, creatine group on training days in 3 servings of 5 grams and 5 grams on non-training days, HMB + Cr group HMB supplement in 3 grams per day and Creatine was consumed in the same way as the creatine group. During the two weeks of training, the HMB group received 1 gr of the supplement daily, the creatine group received 5 gr of the supplement, and the HMB + Cr group received 1 gr of the HMB supplement daily and 5 grams of the creatine supplement. One-way analysis of variance with repeated measures was used to test the hypotheses. The test results showed that in the post-test between weight training groups and HMB (p = 0.000), creatine (p = 0.006) and HMB + Cr (p = 0.000) and in two weeks of inactivity, there was a significant difference in CK between the weight training group and HMB + Cr (p = 0.047). Also between weight training groups and HMB (p = 0.000), HMB + Cr (p = 0.000), creatine and HMB (p = 0.019), creatine and HMB + Cr (p = 0.001) in both Week of inactivity There was a significant difference in LDH between the weight training group and HMB + Cr (p = 0.004), creatine and HMB (p = 0.026), creatine and HMB + Cr (p = 0.001). It seems that 6 weeks of weight training with a combination of HMB and creatine supplement and 2 weeks of non-training can significantly reduce muscle injury indices in male powerlifting athletes. . Manuscript profile
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  7 - The Effect of Different Degrees of Dehydration on Plasma Creatine Kinase and Lactate Dehydrogenase Levels of Professional Wrestlers in Ahvaz
  mehdi bostani reza sheikh
  Despite the proving of the negative effects of dehydration, many athletes use of this strategy yet. The aim of this study was to investigate the effect of dehydration with different degrees on serum levels of enzymes biomarker muscle damage in professional wrestlers in More

  Despite the proving of the negative effects of dehydration, many athletes use of this strategy yet. The aim of this study was to investigate the effect of dehydration with different degrees on serum levels of enzymes biomarker muscle damage in professional wrestlers in Ahvaz city. Among the professional wrestlers in Ahvaz city, after screening, 40 wrestlers were selected and randomly divided into three experimental groups and one control group. Experimental groups underwent dehydration at three levels of mild, moderate and severe. The plasma levels of Creatine Kinase (CK) and Lactate Dehydrogenase (LDH) were measured by enzyme kinetics method. for intragroup comparison and intergroup comparison, were used of the dependent t-test and analysis of variance (ANOVA) test respectively at a significance level of 0.05. The results showed that plasma CK levels increased significantly in the moderate and severe dehydration groups and LDH levels increased only in the severe dehydration group (P <0.05). Also, in the intergroup comparison of CK levels, it was observed that there was a significant difference between the severe dehydration group and other groups, as well as the moderate dehydration group and other groups (P <0.05). But no significant difference was observed between the moderate and severe dehydration groups (P <0.05). Also, the results of comparison between groups of LDH showed that only the difference between the severe dehydration group with other groups was significant (P <0.05) and the difference between the other groups was not significant (P <0.05). According to the results of this study, it is suggested that to prevent the possibility of muscle damage and consequently reduced the exercise performance, avoided the dehydration of more than 1% in one session and if necessary, dehydrate in more sessions and for longer. Manuscript profile