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      • Open Access Article

        1 - Effect of Intensity and Volume of Exercise Training on Serum Levels of Ceruloplasmin and Malondialdehyde in Elite Handball Player Girls
        zahra mehregan Najmeh Rezaeian
        Introduction: Imbalance between the production of free radicals and the antioxidant defense system leads to oxidative stress. The purpose of this study was to investigate the effect of four weeks of high intensity interval training (HIIT) versus four weeks of aerobic tr More
        Introduction: Imbalance between the production of free radicals and the antioxidant defense system leads to oxidative stress. The purpose of this study was to investigate the effect of four weeks of high intensity interval training (HIIT) versus four weeks of aerobic training on serum levels of ceruloplasmin and malondialdehyde in elite handball player girls.Methods: Thirty young handball player girls (mean aged 16.85±1.4 years), with four years of membership in handball team of North Khorasan province, were selected and randomly divided into two groups of training and one control group. Subjects in experimental groups participated in four weeks of HIIT [running at intensity of 95-90 percentage of maximum heart rate and resting intervals of 1-3 minutes running at 60-50 percentage of maximum heart rate] and aerobic training (running at 50-70 percentage of maximum heart rate, 45-60 minutes per session), three sessions per week. The blood samples were taken factors before and 48 hours after last training session to assess blood factors. Data analysis was done by One-way ANOVA, paired t-test, and Pearson correlation, and P<0.05 considered significant.Results: Serum levels of MDA decreased significantly following aerobic training (P=0.044). Moreover, weight (P=0.009), body mass index (BMI) (P=0.002) and body fat percent (P=0.036) decreased significantly following HIIT. Furthermore, aerobic training resulted in significant decline in weight (P=0.008), BMI (P=0.015) and body fat percent (P=0.013).Conclusion: It seems that the volume of training influences on serum levels of MDA; however, ceruloplasmin levels was affected by neither intensity nor volume of training. Manuscript profile
      • Open Access Article

        2 - Serum Levels of Zinc, Copper and Their Carrier Proteins in Cattle with theileriosis
        مجید Fartashvand بهرام Amouoghli Tabrizi علی Hasanpour سید رضا S.J SH Pourhassan یعقوب Haji-Sadeghi
        In this study, 90 cattle with theileriosis and 90 healthy cattle were studied based on clinical and laboratory examination including parasitological and biochemical tests. Special biochemical kits were used for determination of zinc, copper, albumin, calcium, magnesium More
        In this study, 90 cattle with theileriosis and 90 healthy cattle were studied based on clinical and laboratory examination including parasitological and biochemical tests. Special biochemical kits were used for determination of zinc, copper, albumin, calcium, magnesium and ferrous levels in sera. Serum levels of transferin and ceruloplasmin were measured with ELISA and Sunderman & Nomoto method, respectively. The serum level of zinc was significantly decreased in cattle suffering from theileriosis (p<0.01). Serum concentration of copper showed decrease in cattle with theileriosis but it was not significant. The Biochemical findings revealed that cattle infected with theileriosis have significantly lower serum levels of transferin, magnesium, albumin, iron (p<0.01) and calcium (p<0.05). Serum value of ceruloplasmin in sick animals was significantly more than healthy cattle (p<0.05). There was significant relationship between serum level of zinc and ceruloplasmin with PCV and also between serum iron level and parasitemia (p<0.05). Results obtained from measurement of biochemical parameters in serum suggested that reduction of serum zinc and copper may be one of the possible reasons of immunosuppression and incidence of secondary infections in cattle with theileriosis. Therefore use of these trace elements, especially zinc in treatment protocol of infected cattle may be beneficial. Manuscript profile
      • Open Access Article

        3 - Effect of Resveratrol Supplementation on Changes in Serum Levels of Ceruloplasmin and Malondialdehyde in Response to One Session of High Intensity Exercise in Sedentary Young Overweight Men
        mohamad khoramdel najmeh rezaeian
        AbstractAntioxidants are first line of defense against the oxidative stress produced during high intensity exercise. Since, obesity is also related to imbalance of oxidative- antioxidative system of body; purpose of this study was to investigate the effect of 14 days of More
        AbstractAntioxidants are first line of defense against the oxidative stress produced during high intensity exercise. Since, obesity is also related to imbalance of oxidative- antioxidative system of body; purpose of this study was to investigate the effect of 14 days of resveratrol supplementation on changes in serum levels of ceruloplasmin and malondialdehyde in response to one bout of high intensity exercise in sedentary overweight young men. For this purpose, twenty sedentary overweight young men selected and randomly divided into two groups (experimental and control). Subjects in both experimental and control groups participated in one bout of exhaustive exercise (Bruce Test). Then, subjects in experimental group (supplementation) consumed one capsule of 400-mg resveratrol per day for 14 days. In control group (placebo), subject consumed one capsule of 400-mg lactose per day for 14 days. First blood sample was taken before the study and second one was done immediately after Bruce test. At the fifteenth day and at the end of 14 days of supplementation, subjects in both groups perform the exhaustive exercise again and forth blood sample was taken immediately following their performance. Data analysis was done using repeated measures ANOVA, and paired t-test, and P<0.05 was considered statistically significant. Finding showed 14 days of resveratrol supplementation had significant effect on serum levels of ceruloplasmin in response to one bout of high intensity exercise (P=0.043). It seems that 14 days of resveratrol supplementation has a significant effect on the improvement of function of antioxidant system of body in in sedentary overweight young men. Nevertheless, further research is necessary to understand the mediated mechanism.  Manuscript profile