• List of Articles Asthma

      • Open Access Article

        1 - A Study on "Asthma" and "Shamar the Migrant" Novels from Hypertext Tragedy Viewpont
        Sadeq Karim Yahya
        Two novels, "Asthma" and "Shamar the Migrant" by Farhad Heidari Guran have been published between 2008 and 2010. These two novels are two parts of a trilogy which the first part has not yet been published. According to the author three tragedies and a historic More
        Two novels, "Asthma" and "Shamar the Migrant" by Farhad Heidari Guran have been published between 2008 and 2010. These two novels are two parts of a trilogy which the first part has not yet been published. According to the author three tragedies and a historical catastrophe have been narrated in this trio; chemical bombardment of Zardeh, Babayadgar and Nesar Daireh villages in 1988summer, the November 2017 earthquake in Kermanshah and the lives of the helpless and addicted in a rescue camp. The author in this trilogy – which should be called "minority literature" – enjoying the form of Yarsanism, he also paid attention to modern and postmodern arrangements of novel writing as well and applied the trick of blogging in Persian novels for the first time. This article studies the author's methods of applying hypermextual devices various approaches to cyberfeminism. Manuscript profile
      • Open Access Article

        2 - A comparison of perfectionism and uncertainty intolerance dimensions in patients with asthma, IBS, and migraine
        sedighe ebrahem zadeh hasan ahadi omid rezaei norali farokhi farhad jomhuri
        Illnesses of asthma, Irritable Bowel Syndrome and migraine are psychosomatic disorders that nowadays are nominated psycho-physiologic disorders. These illnesses have not been recognized completely. But it is apparent that psychological factors are effective in all of th More
        Illnesses of asthma, Irritable Bowel Syndrome and migraine are psychosomatic disorders that nowadays are nominated psycho-physiologic disorders. These illnesses have not been recognized completely. But it is apparent that psychological factors are effective in all of them. The aim of the present research was to compare the dimensions of perfectionism and intolerance of uncertainty in patients with asthma, IBS and migraine. The sample consisted of 120subjects in four groups: Those who were diagnosed as asthma, IBS and migraine (per 30 subjects) selected from psychiatric, respiratory and gastrointestinal disease clinics in Tehran, and a non-patient group (30 subjects). The participants completed the Dimensions of perfectionism inventory of Hewitt and Fleet and Intolerance of Uncertainty scale of Buher & Dugas. Results showed that the difference of perfectionism mean was significant in patient group. And the difference was significant for intolerance of uncertainty mean (α = 0/ 01). The IBS and migraine groups had higher mean in perfectionism and intolerance of uncertainty. Manuscript profile
      • Open Access Article

        3 - Investigation of 8 weeks of breathing exercise on pulmonary function in patients with asthma
        mitra tajari Iman Ghanbari
        Objectives: Considering the role of regular physical activity on improving lung function at rest, the aim of the present study was the effect of eight weeks of yoga exercises on lung function in people with asthma.Materials and methods: In this semi-experimental study, More
        Objectives: Considering the role of regular physical activity on improving lung function at rest, the aim of the present study was the effect of eight weeks of yoga exercises on lung function in people with asthma.Materials and methods: In this semi-experimental study, 80 patients with asthma, with an average age of 5.40 ± 3.11, were selected purposefully and randomly, and were randomly assigned to two exercise and control groups (each the group of 40 people) were divided. The exercise intervention consisted of eight weeks of yoga exercises with repetition of three sessions per week. Pulmonary function tests included VC and MEF lung volumes, which were evaluated before and after the intervention. The data obtained from the measurement were analyzed by variance analysis using spss 21 software at a significance level of 0.05.Findings: In the pre-test examination, no significant difference was observed between the control and yoga practice groups in VC and MEF volumes. Eight weeks of exercise intervention resulted in significant improvement in VC and MEF volumes (p=0.001 and p=0.002, respectively) compared to before exercise. While in the control group, no significant change was observed in any of the measured variables compared to the pre-test.Conclusion: Yoga exercises can improve lung function in patients with asthma by strengthening respiratory muscles. Manuscript profile
      • Open Access Article

        4 - New Prognostic Index to Detect the Severity of Asthma Automatically Using Signal Processing Techniques of Capnogram
        Mohsen Kazemi Aik Howe Teo
        In this paper, a new prognostic index to detect the severity of asthma by processing capnogram signals is presented. Previous studies have shown significant correlation between the capnogram and asthmatic patient. However, most of them used conventional time-domain meth More
        In this paper, a new prognostic index to detect the severity of asthma by processing capnogram signals is presented. Previous studies have shown significant correlation between the capnogram and asthmatic patient. However, most of them used conventional time-domain methods and based on assumption that the capnogram is a stationary signal. In this study, by using linear predictive coding (LPC) coefficients and autoregressive (AR) modelling (Burg method), the capnogram signals are processed. Then, a number of six features including α1, and α4 from LPC and power spectral density (PSD) parameters through AR modelling are extracted. After that, by means of receiver operating characteristic (ROC) curve, the effectiveness of the extracted features to differentiate between asthmatic and nonasthmatic conditions is justified. Finally, selected features are used in a Gaussian radial basis function (GRBF) network. The output of this network is an integer prognostic index ranging from 1 to 10 (depends on the severity of asthma) with an average good detection rate of 90.15% and an error rate of 9.85%. In the other word, based on the results, sensitivity and specificity of this algorithm are 93.54% and 98.29%, respectively. This developed algorithm is purposed to provide a fast and low-cost diagnostic system to help healthcare professional involved in respiratory care as it would be possible to monitor severity of asthma automatically and instantaneously. Manuscript profile
      • Open Access Article

        5 - A NONLINEAR MATHEMATICAL MODEL FOR ASTHMA: EFFECT OF ENVIRONMENTAL POLLUTION
        NARESHA RAM Agraj Tripathi
      • Open Access Article

        6 - Evaluation and identification of allergenic bands caused by A. alternata, P. citrinum and A. fumigatus in the asthmatic patients using immunoblotting approaches
        Azar Sabokbar Amir Bakhtiari Mojgan Saghazadeh
        Background & Objectives: Several studies have shown that fungi can cause allergenic asthma in the susceptible persons. Among these fungi, Alternaria, Penicillium and Aspergillus species are more common in this cases. This study was performed to detect and to compare More
        Background & Objectives: Several studies have shown that fungi can cause allergenic asthma in the susceptible persons. Among these fungi, Alternaria, Penicillium and Aspergillus species are more common in this cases. This study was performed to detect and to compare allergenic bands in A.alternata, P.citrinum and A.fumigatus. Materials & Methods: This cross-sectional study was performed on 48 patients afflicted to asthma and 22 healthy controls. The fungi were grown and their extract crude were obtained using the liquid nitrogen. The protein fractions were isolated by SDS-PAGE and after electrotransfering and transfer of the bands into the nitrocellulose membrane, the proteins were used for immunoblotting against the sera obtained from patients and controls. Results: Based on the immunobloting test, 6 protein allergenic bands for A. alternata (49-115 kDa), 4 protein bands for A. fumigatus (57-112 kDa) and 5 protein bands for P. citrinum (37-127 kDa) are detected in these samples. Conclusion: The highest amount of allergic band belonged to A. alternate. The bands with higher molecular weights were more effective in stimulation of IgE. Manuscript profile
      • Open Access Article

        7 - Molecular identification gene of the Helicobacter pylori neutrophil activating protein effective in controlling allergic asthma by PCR method
        Alireza Khaleghi Khorrami Sanaz Mehmazi Rasul Shukri Seyyed Shamsadin Athari
      • Open Access Article

        8 - Investigating the effect of mesenchymal stem cells on airway hyper-responsiveness in asthma
        Kambiz Moghaddasi Saeed Hesaraki Farnoosh Arfaee Seyyed Shamsadin Athari
        Asthma is a lung disease characterized by eosinophilic inflammation, mucus secretion, airway hyper-responsiveness (AHR), and airway obstruction. AHR is a crucial factor in asthma. Mesenchymal stem cells (MSCs) have a regulatory effect on the immune response and may be u More
        Asthma is a lung disease characterized by eosinophilic inflammation, mucus secretion, airway hyper-responsiveness (AHR), and airway obstruction. AHR is a crucial factor in asthma. Mesenchymal stem cells (MSCs) have a regulatory effect on the immune response and may be useful in treating asthma. MSCs have low immunogenicity and are considered safe for application. Additionally, a study was conducted to investigate the effect of MSCs on controlling AHR in an asthma model. MSCs were isolated and used to treat asthmatic male BALB/c mice. To produce an animal model of asthma, the mice were sensitized and challenged with OVA. On days 30 and 40, to measure AHR, a Methacholine challenge test was performed to determine the Penh value. AHR was recorded and analyzed. Treatment of asthmatic mice with MSCs resulted in a significant difference (p<0.05) in controlling AHR during the MCh challenge test. MSCs are almost non-immunogenic and can be used to treat asthma and control AHR. The use of MSCs as an anti-asthma treatment presents a new and applicable strategy for controlling AHR in asthma. Manuscript profile
      • Open Access Article

        9 - Phagocytic Activity and IL-1 Alpha Levels for Asthma Patients
        Amna Esmaeel Al-araji Haethem Qassim Mohammad Roaa Mohammed Chessab
      • Open Access Article

        10 - Low Serum Potassium Level and Its Effects on the Severity and the Rate of Hospitalization in Asthmatic Adults
        W. J. Majid Hanaa S. Khadem Tayseer A. Talab , Mahdi M. Thuwaini
      • Open Access Article

        11 - Moderating role of experiential avoidance in the relationship between anxiety sensitivity and perceived stress
        Somaye Rajabpour Farkhani Masod GHolamali Lavasani Gholamali Afrooz
        It is traditional that birth weight could be considered as the only mean of assessing pregnancy outcome; and is a reliable indicator of fetal health and maturity, and also, the easiest measurement that is properly accurate and can be used in different conditions around More
        It is traditional that birth weight could be considered as the only mean of assessing pregnancy outcome; and is a reliable indicator of fetal health and maturity, and also, the easiest measurement that is properly accurate and can be used in different conditions around the world. Studies show that infants with appropriate birth weight have relatively low mortality rates even in adverse environmental conditions. This study aims to evaluate the effectiveness of programs consisted of psychological interventions on birth weight in the city of Ghoochan. Therefore, in a semi-experimental research with pre-test, post-test, and control group design, 25 parents who referred to the city&rsquo;s health centres for prenatal physical examinations and volunteered to receive psychological intervention were selected through convenience sampling method and assigned to experimental group and were matched with 25 parents, as control group, who referred to the same health centres but were not willing to volunteer to receive psychological interventions. The experimental group received 15 sessions of psychological education and interventions. The newborns of subjects in both groups were measured after birth for height, weight, head circumference, and Apgar score. The comparison of these measurements revealed that psycho-educational interventions are meaningfully effective on improvement of these quantities. Thus, it can be concluded that psycho-educational interventions can have a significant impact on birth weight among infants. Manuscript profile
      • Open Access Article

        12 - Investigation of the effect of Helicobacter pylori neutrophil-activating protein on leukotriene C4, B4 levels and airway inflammation in an allergic asthma mouse model.
        Alireza  Khaleghi khorrami
        Background & Aim: Helicobacter pylori neutrophil-activating protein (HP-NAP) acts as an immunogen to elicit antigenic responses or an immunomodulator to regulate T-cell immunity. This protein can lead to a Th2 response, which may result in an allergic response or a Th1 More
        Background & Aim: Helicobacter pylori neutrophil-activating protein (HP-NAP) acts as an immunogen to elicit antigenic responses or an immunomodulator to regulate T-cell immunity. This protein can lead to a Th2 response, which may result in an allergic response or a Th1 response. It is also likely to affect the production of leukotrienes C4, B4 and finally asthma. The objective of this study is to examine the impact of HP-NAP on the concentration of leukotrienes C4 and B4 in an allergic asthma model in mice and to compare this with the effects of Helicobacter pylori. Materials & Methods: Firstly, the Helicobacter pylori standard strain and HP-NAP peptide were prepared in accordance with the methodology outlined in a previous study. Subsequently, 40 adult Blab c 6 to 8-week-old male mice were prepared for modelling and developing allergic asthma and were divided into four groups of 10. These mice were selected for further study to investigate the changes in the aforementioned leukotrienes. Results: demonstrated that the level of leukotrienes C4 and B4, as measured using the ELISA method, was significantly elevated in the asthmatic group compared to the healthy group. While the treatments with Helicobacter and HP-NAP did not result in a significant decrease in the levels of C4 and B4 compared to the asthmatic group, Conclusion: In light of the more pronounced effects of HP-NAP compared to Helicobacter itself in reducing the level of C4 and B4 leukotrienes, HP-NAP was able to reduce the level of C4 and B4 leukotrienes in asthmatic animals. However, this reduction was not statistically significant when compared to the asthmatic group. Therefore, further studies are recommended. Manuscript profile