List of Articles Antimicrobial agents

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  1 - Study of antioxidan and antimicrobial effects of aqueous and alcoholic extract of plant ( Lawsonia inermis, punica granatum, walnut, Myrtus) on gram positive and gram negative bacteria
  simin khosravi zahra rezayatmand mozhgan ghiasian
  Recently , due to the resistance of bacterial pathogens to the detection of new antimicrobials, much attention has been paid. In the present study, the antimicrobial properties of four extracts of leafy leafy leaves, henna leaves, walnut shells and pomegranate peel on t More

  Recently , due to the resistance of bacterial pathogens to the detection of new antimicrobials, much attention has been paid. In the present study, the antimicrobial properties of four extracts of leafy leafy leaves, henna leaves, walnut shells and pomegranate peel on three gram-positive bacteria, Staphylococcus aureus, Staphylococcus epidermidis and Bacillus subtilis, and two gram-negative bacteria of Escherichia coli and Pseudomonas aeruginosa were studied. it placed. Antimicrobial effect of the alcoholic and aqueous extract of these plants was studied by diffusion and well discarding method by measuring the non-growth aura's diameter and the minimum inhibitory concentration was investigated by ELISA method. The results show that in two methods, diffusion discs and wells in alcoholic and aqueous extracts have the highest effect on Staphylococcus epidermidis bacterium and have the least effect on E. coli bacteria. The minimum amount of MIC for alcoholic extract is 31.25 and MBC 54.25 mg / ml, which is related to Escherichia coli bacteria. The results measurements of total phenolic compounds, flavonoids and tannins also indicate that the highest amount of this product is in the concentration of 500 mg / ml of the extract of plants. Also, the amount of antioxidant activity in the alcoholic extract is about twice as much as the aqueous extract. The results of this study indicate that the combination of extracts of plants, especially alcoholic extract, has a more antibacterial effect than the aqueous extract, which can be due to the presence of more antibacterial compounds in the extract. Manuscript profile
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  2 - One-pot Synthesis of 2-amino-4H-chromene Derivatives as Potential Antimicrobial Agents using DABCO-CuCl Complex as an Effective Catalyst
  Bita Baghernejad Samaneh Koosha
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  3 - بررسی اثر ضدباکتریایی و فیتوشیمیایی عصاره متانولی و استونی گونه‌های Cupressus sempervirens و Juniperus excelsa بر برخی بیماری‌های مهم غذایی
  سیما یزدانی منیر دودی زهرا رضایتمند لادن رحیم زاده ترابی
  10.30495/medherb.2023.703159
  Background & Aim: The unfettered usage of antibiotics has engendered a mounting resistance of bacteria to these agents, thereby necessitating the discovery and development of novel compounds and medications to a greater extent than previously. The focal point of thi More

  Background & Aim: The unfettered usage of antibiotics has engendered a mounting resistance of bacteria to these agents, thereby necessitating the discovery and development of novel compounds and medications to a greater extent than previously. The focal point of this research was to explore the chemical constituents of acetone and methanol-extracted samples of Cupressus sempervirens and Juniperus excelsa, as well as their potential inhibitory actions against a prevalent food-borne pathogen.Experimental: This experimental investigation was conducted on standard strains of Staphylococcus aureus (PTCC 1430), Bacillus cereus (PTCC 1431), Listeria monocytogenes (PTCC 1298), Escherichia coli (PTCC 1399), and Shigella dysentery (PTCC 1188). Following the preparation of methanol and acetone extracts derived from Juniperus excelsa and Cupressus sempervirens using Clevenger apparatus, the antimicrobial efficacy was assessed by both qualitative agar well diffusion method and quantitative macrodilution method. The active constituents present in the methanol and acetone extracts of the plants were identified by gas chromatography-mass spectrometry (GC/MS) analytical method. Means were compared with Duncan's test at the 5% probability level.Results: The findings of this investigation pertaining to the antimicrobial potency of the extracts, ascertained via the qualitative agar well diffusion method, indicated its efficacy against Gram-positive strains including S. aureus and B. cereus. The methanol extracts of the J. Excelsa were found to produce smaller inhibition zones on the tested bacteria compared to other plant extracts. The highest sensitivity to the acetone extract of C. sempervirens and J. excelsa observed in S. aureus and B. cereus. The extracts obtained from the two plant did not demonstrate any discernible impact on the Gram-negative bacteria that are commonly associated with foodborne pathogens. The findings obtained through gas chromatography-mass spectrometry (GC/MS) indicated the presence of efficacious components such as Benzene 1,2,4,5-tetramethyl, and Cyclopropane cyclopenta in J. excels extract. The acetone extract of J. excelsa showed more potent antimicrobial constituents than its methanolic counterpart. It is anticipated that in forthcoming times, the acetone extract derived from this botanical specimen may be employed to prevent bacterial-induced foodborne illnesses.Recommended applications/industries: Duo to the existence of a range of bioactive compounds in the acetone extracts obtained from C. sempervirens and J. excels, these extracts have the potential to be used against the development of foodborne infections and diseases caused by bacterial agents. Manuscript profile
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  4 - اثر تیمار کوتاه مدت با نانو ذرات نقره و محلول گلجایی ساکارز روی پیری گل و برگ شاخه بریده رز
  خدیجه آل کثیر رحیم نقش بند حسنی علیرضا مطلبی آذر
  این آزمایش برای ارزیابی اثر تیمار کوتاه مدت نانو ذرات نقره در غلظت­ های صفر، 4، 25، 75 و 125 میلی­ گرم در لیتر روی گل شاخه بریدنی رز رقم ʼهای اند مجیکʻ بدنبال نگهداری در محلول ساکارز با غلظت­ های صفر، 2 و 3 درصد از نظر عمر گلجایی و برخی از صفات فیزیولوژیکی پ More

  این آزمایش برای ارزیابی اثر تیمار کوتاه مدت نانو ذرات نقره در غلظت­ های صفر، 4، 25، 75 و 125 میلی­ گرم در لیتر روی گل شاخه بریدنی رز رقم ʼهای اند مجیکʻ بدنبال نگهداری در محلول ساکارز با غلظت­ های صفر، 2 و 3 درصد از نظر عمر گلجایی و برخی از صفات فیزیولوژیکی پس از برداشت آن انجام شد. این تحقیق به شکل آزمایش فاکتوریل در قالب طرح کاملا تصادفی با سه تکرار برای هر تیمار اجرا شد. آزمایش تحت شرایط دمای 2 ± 23 درجه سانتی­گراد، رطوبت نسبی 5±60 درصد و با شدت نوری محیط 12 میکرو مول در مترمربع درثانیه به مدت 12 ساعت توسط لامپ­ های فلورسنت انجام شد. نتایج نشان داد که تیمار 125 میلی­ گرم در لیتر نانو ذرات نقره همرا با ساکارز دو درصد و بدون ساکارز بیشترین تاثیر را در کنترل باکتری­ های انتهای ساقه را داشت. تیمار کوتاه مدت نانو ذرات نقره در کلیه غلظت­ ها سبب بهبود جذب محلول، حفظ رطوبت نسبی شاخه، بهبود باز شدن گل و شاخص فلورسانس کلروفیل برگ (Fv/Fm) در مقایسه با تیمار شاهد گردید. بیشترین میزان باز شدگی گل با درشت­ترین اندازه گل در تیمار 75 میلی­ گرم در لیتر نانوذرات همراه با ساکارز 2 درصد در روز نهم عمر گلجایی مشاهده گردید. کمترین میزان عمر گلجایی در تیمارهای آب مقطر به تنهایی و همراه با ساکارز بود. بیشترین میزان عمر گلجایی در تیمارهای 75 و 125 میلی­ گرم در لیتر نانو ذرات نقره بدون ساکارز و با ساکارز در مقایسه با سایر تیمارها مشاهده گردید.  Manuscript profile
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  5 - Evaluation of antifungal and antibacterial properties of palladium (II) Schiff base complex against common pathogenic strains between humans and aquatic
  Mohammadreza Moghaddam-manesh Somaye Shahriari Sara Hosseinzadegan
  10.30495/jacr.2022.1935692.1962
  Metal complexes containing Schiff base ligand are compounds that have biological effects such as antifungal, antibacterial, anti-malarial, anti-inflammatory, anti-viral and anti-fever properties. These compounds are also used in various industries. In this study, Pallad More

  Metal complexes containing Schiff base ligand are compounds that have biological effects such as antifungal, antibacterial, anti-malarial, anti-inflammatory, anti-viral and anti-fever properties. These compounds are also used in various industries. In this study, Palladium (II) Schiff base complex with the proposed formula C14H24N4O2Cl2Pd was synthesized by the method reported in Zabol University and used to investigate the antimicrobial effects. Antimicrobial activity such as antibacterial activity against pathogenic strains common between aquatic and human inclusive Loctococcus garvieae and Edwardsiella tarda strains and antifungal activity inclusive Aspergillus fumigatus and Candida albicans were performed according to CLSI standard and the results were reported based on inhibition zone diameter (IZD), minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC). Based on the results, the studied complex showed MIC concentrations of 32 μg/ml and 64 μg/ml on the Edwardsiella tarda and Loctococcus garvieae, respectively. The MIC concentrations on Aspergillus fumigatus and Candida albicans, respectively, 512 μg/ml and 1024 μg/ml were observed. The results of this study showed that the effect of Pd (II) Schiff base complex has strong antimicrobial properties and has a better effect than some commercial drugs. Manuscript profile