List of Articles پاروویروس

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  1 - Evaluation of changes in blood antioxidants in dogs with parvovirus infection
  arghavan zarandi Bahram Amouoghli Tabrizi siamak mashhahirafei
  10.30495/jvcp.2022.1955954.1365
  Canine parvovirus (CPV-1) is a highly contagious viral disease in dogs that usually causes acute gastrointestinal disease in puppies. The disease is more common in dogs aged 6 weeks to 6 months. Antioxidants are compounds that prevent oxidation. Oxidation is a chemical More

  Canine parvovirus (CPV-1) is a highly contagious viral disease in dogs that usually causes acute gastrointestinal disease in puppies. The disease is more common in dogs aged 6 weeks to 6 months. Antioxidants are compounds that prevent oxidation. Oxidation is a chemical reaction that can produce free radicals, thus leading to chain reactions that may damage the cells of living organisms. Antioxidants such as thiol or ascorbic acid (vitamin C) interrupt these chain reactions. Due to the prevalence of parvovirus in dogs and little research on the effect of antioxidants in controlling or exacerbating the disease, this study was performed to determine the effect of antioxidants in the treatment of this disease. In this study, blood samples were taken from 50 dogs, including 25 dogs with parvovirus disease and 25 healthy dogs with the disease, followed by catalase, glutathione peroxidase, superoxide dismutase, malondialdehyde and total antioxidant capacity. Rendox kit spectrophotometry was measured. Statistical results to t-test method and SPSS software version 23 were analyzed. The results showed that the enzymes of catalase, glutathione peroxidase, superoxide dismutase and total antioxidant capacity in the treatment group compared to the control group had a statistically significant decrease and the amount of malondialdehyde increased statistically (P <0.05). The results show that dogs with parvovirus infection are affected by the antioxidant system, so it should be considered in treatment and prevention. Manuscript profile
• Open Access Article
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  2 - Assessment of hematological parameters and some biochemical parameters in dogs infected with parvovirus
  Boshra sadat Bani hashemi abbas kalantari
  10.30495/vmj.2024.2000080.1029
  Parvovirus in dogs causes a fatal disease with the effects of destruction of hematopoietic precursor cells and involvement of various organs and parts such as intestinal epithelial cells, thymus and lymph nodes. To conduct this research sampling was done of 25 dogs with More

  Parvovirus in dogs causes a fatal disease with the effects of destruction of hematopoietic precursor cells and involvement of various organs and parts such as intestinal epithelial cells, thymus and lymph nodes. To conduct this research sampling was done of 25 dogs with symptoms of gastroenteritis wich were positive with rapid test for canine parvovirus detection. After taking blood samples, the hematological and biochemical factors of serum were analyzed using statistical methods (Shapiro-Wilk and t-test) in comparison with reference values. The obtained results showed that the number of red and white blood cells, the number of neutrophils and lymphocytes, the concentration of hemoglobin and the percentage of hematocrit in dogs infected with parvovirus were significantly lower than the reference values (P<0.001). Also, the activities of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes, blood urea nitrogen and serum creatinine of infected dogs were significantly higher than the reference values (P<0.001).the results of this study indicated the destructive effect of parvovirus on the desired indicators, and knowing the status of the blood panel can be of great help for the correct treatment of the disease. Manuscript profile